Personalised nutrition and health Page 1 the bmj | BMJ 2018;361:k2173 | doi: 10.1136/bmj.k2173
1 Science and PoliticS of nutrition Personalised nutrition and health Jose Ordovas and …

The gut microbiome is emerging as an important contributor to both cardiovascular disease
risk and metabolism of xenobiotics. Alterations in the intestinal microbiota are associated …

Background: The gut microbiota-dependent metabolite phenylacetylgutamine (PAGln) is
both associated with atherothrombotic heart disease in humans, and mechanistically linked …

Diet-related risk factors and physical inactivity are among the leading risk factors for
disability and are responsible for a large proportion of the burden of chronic non …

Background: Predictions of cardiovascular disease risks based on health records have long
attracted broad research interests. Despite extensive efforts, the prediction accuracy has …

Over time, the relationship between diet and health has aroused great interest, since
nutrition can prevent and treat several diseases. It has been demonstrated that general …

Background: DNA methylation patterns associated with habitual diet have not been well
studied. Methods: Diet quality was characterized using a Mediterranean-style diet score and …

If unifying principles could be revealed for how the same genome encodes different
eukaryotic cells and for how genetic variability and environmental input are integrated to …

The increased life expectancy and the expansion of the elderly population are stimulating
research into aging. Aging may be viewed as a multifactorial process that results from the …

Branched chain amino acids (BCAAs) are essential for protein homeostasis, energy
balance, and signaling pathways. Changes in BCAA homeostasis have emerged as pivotal …