Carboranes in drug discovery, chemical biology and molecular imaging

A Marfavi, P Kavianpour, LM Rendina - Nature Reviews Chemistry, 2022 - nature.com
There exists a paucity of structural innovation and limited molecular diversity associated with
molecular frameworks in drug discovery and biomolecular imaging/chemical probe design …

Storing energy with molecular photoisomers

Z Wang, P Erhart, T Li, ZY Zhang, D Sampedro, Z Hu… - Joule, 2021 - cell.com
Some molecular photoisomers can be isomerized to a metastable high-energy state by
exposure to light. These molecules can then be thermally or catalytically converted back to …

The Rise of Boron-Containing Compounds: Advancements in Synthesis, Medicinal Chemistry, and Emerging Pharmacology

RJ Grams, WL Santos, IR Scorei, A Abad-García… - Chemical …, 2024 - ACS Publications
Boron-containing compounds (BCC) have emerged as important pharmacophores. To date,
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …

A Strategy for Selective Catalytic B–H Functionalization of o-Carboranes

Z Qiu, Z Xie - Accounts of Chemical Research, 2021 - ACS Publications
Conspectus Carboranes are a class of polyhedral carbon–boron molecular clusters
featuring three-dimensional aromaticity, which are often considered as 3D analogues of …

Peptide-drug conjugates and their targets in advanced cancer therapies

P Hoppenz, S Els-Heindl, AG Beck-Sickinger - Frontiers in chemistry, 2020 - frontiersin.org
Cancer became recently the leading cause of death in industrialized countries. Even though
standard treatments achieve significant effects in growth inhibition and tumor elimination …

Boron chemistry for medical applications

F Ali, NS Hosmane, Y Zhu - Molecules, 2020 - mdpi.com
Boron compounds now have many applications in a number of fields, including Medicinal
Chemistry. Although the uses of boron compounds in pharmacological science have been …

Electrochemistry and photoluminescence of icosahedral carboranes, boranes, metallacarboranes, and their derivatives

R Núñez, M Tarrés, A Ferrer-Ugalde… - Chemical …, 2016 - ACS Publications
Icosahedral boranes, carboranes, and metallacarboranes are extraordinarily robust
compounds with desirable properties such as thermal and redox stability, chemical …

Recent Progress in the Development of Solid‐State Luminescent o‐Carboranes with Stimuli Responsivity

J Ochi, K Tanaka, Y Chujo - Angewandte Chemie International …, 2020 - Wiley Online Library
Abstract o‐Carborane, a cluster compound containing boron and adjacent carbon atoms,
displays intriguing luminescent properties. Recently, compounds containing o‐carborane …

Nonclassical Applications of closo-Carborane Anions: From Main Group Chemistry and Catalysis to Energy Storage

SP Fisher, AW Tomich, SO Lovera… - Chemical …, 2019 - ACS Publications
Classically closo-carborane anions, particularly [HCB11H11]− and [HCB9H9]−, and their
derivatives have primarily been used as weakly coordinating anions to isolate reactive …

Boron cluster compounds as new chemical leads for antimicrobial therapy

K Fink, M Uchman - Coordination Chemistry Reviews, 2021 - Elsevier
Boron cluster compounds are inorganic compounds with chemical compositions and
structures vastly different from those of organic compounds, albeit with the ability to form a …