Calcineurin as a multifunctional regulator: unraveling novel functions in fungal stress responses, hyphal growth, drug resistance, and pathogenesis

PR Juvvadi, F Lamoth, WJ Steinbach - Fungal biology reviews, 2014 - Elsevier
Calcineurin signaling plays diverse roles in fungi in regulating stress responses,
morphogenesis and pathogenesis. Although calcineurin signaling is conserved among …

[HTML][HTML] Fission yeast cell wall biosynthesis and cell integrity signalling

P Pérez, JCG Cortés, J Cansado, JC Ribas - The Cell Surface, 2018 - Elsevier
The cell wall is a structure external to the plasma membrane that is essential for the survival
of the fungi. This polysaccharidic structure confers resistance to the cell internal turgor …

Chaperone-facilitated aggregation of thermo-sensitive proteins shields them from degradation during heat stress

M Cabrera, S Boronat, L Marte, M Vega, P Pérez… - Cell Reports, 2020 - cell.com
Cells have developed protein quality-control strategies to manage the accumulation of
misfolded substrates during heat stress. Using a soluble reporter of misfolding in fission …

The fission yeast cell integrity pathway: a functional hub for cell survival upon stress and beyond

J Cansado, T Soto, A Franco, J Vicente-Soler… - Journal of Fungi, 2021 - mdpi.com
The survival of eukaryotic organisms during environmental changes is largely dependent on
the adaptive responses elicited by signal transduction cascades, including those regulated …

Paxillin-mediated recruitment of calcineurin to the contractile ring is required for the correct progression of cytokinesis in fission yeast

R Martín-García, V Arribas, PM Coll, M Pinar, RA Viana… - Cell reports, 2018 - cell.com
Paxillin is a scaffold protein that participates in focal adhesion signaling in mammalian cells.
Fission yeast paxillin ortholog, Pxl1, is required for contractile actomyosin ring (CAR) …

Rho1 GTPase and PKC ortholog Pck1 are upstream activators of the cell integrity MAPK pathway in fission yeast

L Sanchez-Mir, T Soto, A Franco, M Madrid, RA Viana… - PLoS …, 2014 - journals.plos.org
In the fission yeast Schizosaccharomyces pombe the cell integrity pathway (CIP)
orchestrates multiple biological processes like cell wall maintenance and ionic homeostasis …

LowTempGAL: a highly responsive low temperature-inducible GAL system in Saccharomyces cerevisiae<?mode longmeta?>

Z Lu, Q Shen, NC Bandari, S Evans… - Nucleic Acids …, 2024 - academic.oup.com
Temperature is an important control factor for biologics biomanufacturing in precision
fermentation. Here, we explored a highly responsive low temperature-inducible genetic …

A novel checkpoint pathway controls actomyosin ring constriction trigger in fission yeast

T Edreira, R Celador, E Manjon, Y Sanchez - Elife, 2020 - elifesciences.org
In fission yeast, the septation initiation network (SIN) ensures temporal coordination
between actomyosin ring (CAR) constriction with membrane ingression and septum …

Calcineurin modulates growth, stress tolerance, and virulence in Metarhizium acridum and its regulatory network

Y Cao, M Du, S Luo, Y Xia - Applied microbiology and biotechnology, 2014 - Springer
Calcineurin is highly conserved and regulates growth, conidiation, stress response, and
pathogenicity in fungi. However, the functions of calcineurin and its regulatory network in …

Feedback regulation of SIN by Etd1 and Rho1 in fission yeast

M Alcaide-Gavilán, A Lahoz, RR Daga, J Jimenez - Genetics, 2014 - academic.oup.com
In fission yeast, the septation initiation network (SIN) is thought to promote cytokinesis by
downstream activation of Rho1, a conserved GTPase that controls cell growth and division …