PJ Hesketh - New England Journal of Medicine, 2008 - Mass Medical Soc
New insights into the pathophysiology of chemotherapy-induced nausea and vomiting, a better understanding of patients at risk, and the availability of new antiemetic agents have all …
R Gralla, M Lichinitser, S Van Der Vegt, H Sleeboom… - Annals of …, 2003 - Elsevier
Background Although all first-generation 5-HT 3 receptor antagonists demonstrate efficacy in preventing acute chemotherapy-induced nausea and vomiting (CINV), effective …
RJ Gralla, D Osoba, MG Kris, P Kirkbride… - Journal of Clinical …, 1999 - Citeseer
THE GOAL OF ANTIEMETIC therapy is to prevent nausea and vomiting completely. This goal is achieved for many patients receiving chemotherapy or radiation therapy, and is …
RM Navari, CK Nagy, SE Gray - Supportive Care in Cancer, 2013 - Springer
Purpose Olanzapine has been shown to be a safe and effective agent for the prevention of chemotherapy-induced nausea and vomiting (CINV). Olanzapine may also be an effective …
In the mid-1980s it was discovered that serotonin (5-hydroxytryptamine; 5-HT) was at least partially responsible for producing chemotherapy-induced nausea and vomiting. It was …
FM Schnell - The oncologist, 2003 - academic.oup.com
Nausea and vomiting are two of the most feared side effects of cancer chemotherapy and radiotherapy. Chemotherapy-induced nausea and vomiting can be broadly categorized as …
I Sekine, Y Segawa, K Kubota, T Saeki - Cancer science, 2013 - Wiley Online Library
Chemotherapy‐induced nausea and vomiting (CINV) is one of the most problematic adverse events that affects the well‐being of cancer patients. Risk factors for CINV and its elimination …
RM Stern, KL Koch, P Andrews - 2011 - books.google.com
Nausea is a complex sensation that results from the interaction of certain fixed biological factors, such as gender, with changeable psychological factors, such as anxiety. This is the …
PJ Hesketh - Cancer investigation, 2000 - Taylor & Francis
Abstract Since their introduction, 5-HT3 receptor antagonists have become the agents of choice in the prevention of acute chemotherapy-induced nausea and vomiting and are …