Trillions of microbes inhabit the human gut, not only providing nutrients and energy to the
host from the ingested food, but also producing metabolic bioactive signaling molecules to …

Acetylcholinesterase (AChE) plays an important role in the pathogenesis of
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …

The nicotinic acetylcholine receptor (nAChR) belongs to a superfamily of pentameric ligand-
gated ion channels involved in many physiologic and pathologic processes. Among …

The effects of estrogens are pleiotropic, affecting multiple bodily systems. Changes from the
body's natural fluctuating levels of estrogens, through surgical removal of the ovaries …

Chemobrain refers to a common sequelae experienced by 15–80% of cancer patients
exposed to chemotherapeutics. The antineoplastic agent doxorubicin (DOX) has been …

Genistein is a naturally occurring polyphenolic molecule in the isoflavones group which is
well known for its neuroprotection. In this review, we summarize the efficacy of genistein in …

With the increasing aging population worldwide, the incidence of senile cognitive
impairment (CI) is increasing, posing a serious threat to the health of elderly persons …

Huntington's disease (HD), a neurodegenerative disease, normally starts in the prime of
adult life, followed by a gradual occurrence of characteristic psychiatric disturbances and …

Alzheimer's disease is one of severe neurological diseases for which no effective treatment
is currently available. The use of genistein (5, 7-dihydroxy-3-(4-hydroxyphenyl)-4H-1 …

Genistein is the simplest secondary metabolite in soybeans and belongs to a group of
compounds called isoflavones. It is a phytoestrogen and it makes up more than 60% of soy …