Violent conflicts claim lives, disrupt livelihoods, and halt delivery of essential services, such
as health care and education. Health systems are often devastated in conflicts as health …

Background The understanding of the epidemiology of severe malaria in African children
remains incomplete across the spectrum of Plasmodium falciparum transmission intensities …

Background The criteria for defining severe malaria have evolved over the last 20 years. We
aimed to assess the strength of association of death with features currently characterizing …

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Background Mortality from severe pediatric falciparum malaria appears low in Oceania but
Plasmodium vivax is increasingly recognized as a cause of complications and death. The …

Abstract Background: The Lives Saved Tool (LiST) model was developed to estimate the
impact of the scale-up of child survival interventions on child mortality. New advances in …

Severe malaria defines individuals at increased risk of death from their infection. Proposed
pathogenic mechanisms include parasite sequestration, inflammation, and endothelial …

Background Cerebral malaria (CM) is a neuropathology which remains one of the deadliest
forms of malaria among African children. The kinetics of the pathophysiological mechanisms …

Malaria remains a challenging diagnosis with variable clinical presentation and a wide
spectrum of disease severity. Using a structured case report form, we prospectively …

Background Although global malaria mortality is declining, estimates may not reflect better
inpatient management of severe malaria (SM) where reported case fatality rates (CFRs) vary …