A number of environmental factors have been associated with the development of IBD.
Alteration of the gut microbiota, or dysbiosis, is closely linked to initiation or progression of …

Epigenetic modifications are among the most important mechanisms by which
environmental factors can influence early cellular differentiation and create new phenotypic …

Obesity is associated with low-grade chronic inflammation. Indeed, adipose tissues (AT) in
obese individuals are the former site of progressive infiltration by pro-inflammatory immune …

The prevalence of obesity, especially in women of child‐bearing age, is a global health
concern. In addition to increasing the immediate risk of gestational complications, there is …

Key points Maternal obesity has been associated with shifts in intestinal microbiota, which
may contribute to impaired barrier function Impaired barrier function may expose the …

All important developmental milestones are accomplished during the fetal stage, and
nutrient fluctuation during this stage produces lasting effects on offspring health, so called …

Fibrosis is a serious condition complicating chronic inflammatory processes affecting the
intestinal tract. Advances in this field that rely on human studies have been slow and …

Background Increasing evidence suggests exposure to adverse conditions in intrauterine
life may increase the risk of developing attention-deficit/hyperactivity disorder (ADHD) in …

Intrauterine growth restriction (IUGR) is a complex global healthcare issue. Concerted
research and clinical efforts have improved our knowledge of the neurodevelopmental …

It is already well-known that visceral adipose tissue is inseparably related to the
pathogenesis, activity, and general outcome of inflammatory bowel disease (IBD). We are …