The three human monocyte subsets: implications for health and disease

KL Wong, WH Yeap, JJY Tai, SM Ong, TM Dang… - Immunologic …, 2012 - Springer
Human blood monocytes are heterogeneous and conventionally subdivided into two
subsets based on CD16 expression. Recently, the official nomenclature subdivides …

Importance of disrupted intestinal barrier in inflammatory bowel diseases

SY Salim, JD Söderholm - Inflammatory bowel diseases, 2011 - academic.oup.com
The current paradigm of inflammatory bowel diseases (IBD), both Crohn's disease (CD) and
ulcerative colitis (UC), involves the interaction between environmental factors in the …

Dendritic cells in intestinal homeostasis and disease

M Rescigno, A Di Sabatino - The Journal of clinical …, 2009 - Am Soc Clin Investig
DCs are specialized APCs that orchestrate innate and adaptive immune responses. The
intestinal mucosa contains numerous DCs, which induce either protective immunity to …

Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16-monocyte subsets

P Ancuta, KY Liu, V Misra, VS Wacleche, A Gosselin… - BMC genomics, 2009 - Springer
Background Human peripheral blood monocytes (Mo) consist of subsets distinguished by
expression of CD16 (FCγRIII) and chemokine receptors. Classical CD16-Mo express CCR2 …

Securing the immune tightrope: mononuclear phagocytes in the intestinal lamina propria

C Varol, E Zigmond, S Jung - Nature Reviews Immunology, 2010 - nature.com
The intestinal landscape comprises the host's own tissue and immune cells, as well as a
diverse intestinal microbiota. Intricate regulatory mechanisms have evolved to maintain …

Functional specialization of human circulating CD16 and CD1c myeloid dendritic-cell subsets

D Piccioli, S Tavarini, E Borgogni, V Steri… - Blood, The Journal …, 2007 - ashpublications.org
Human blood contains 2 populations of dendritic cells (DCs): plasmacytoid and myeloid
(mDC). mDCs are subdivided into 3 subsets using the surface markers CD16, CD1c, and …

Involvement of intestinal dendritic cells in oral tolerance, immunity to pathogens, and inflammatory bowel disease

BL Kelsall, F Leon - Immunological reviews, 2005 - Wiley Online Library
Dendritic cells (DCs) are composed of a family of cells, now recognized to be essential for
innate and acquired immunity. DCs at mucosal surfaces have a particular capacity to induce …

Expression of VAChT and 5-HT in Ulcerative colitis dendritic cells

S Pergolizzi, G Rizzo, A Favaloro, A Alesci, S Pallio… - Acta histochemica, 2021 - Elsevier
Ulcerative colitis is a chronic inflammatory condition of the gastrointestinal tract that can
affect people of worldwide. In contrast with Crohn's disease, that can relate the entire …

A β-oxidation-resistant lipoxin A4 analog treats hapten-induced colitis by attenuating inflammation and immune dysfunction

S Fiorucci, JL Wallace, A Mencarelli… - Proceedings of the …, 2004 - National Acad Sciences
Lipoxins and aspirin-triggered 15-epi-lipoxins (ATL) are counter-regulatory eicosanoids with
potent antiinflammatory actions. Oral efficacy and mechanism of action of ZK-192, a β …

Leukotriene pathways and in vitro adenotonsillar cell proliferation in children with obstructive sleep apnea

E Dayyat, LD Serpero, L Kheirandish-Gozal… - Chest, 2009 - Elsevier
Introduction The abundant expression of leukotrienes (LTs) and their receptors in
adenotonsillar tissues of children with obstructive sleep apnea (OSA) suggest that LT …