A new insight into the synthesis and biological activities of pyrazole based derivatives

S Mor, M Khatri, R Punia, S Nagoria… - Mini-Reviews in …, 2022 - ingentaconnect.com
This review aims to collate literature work reported by researchers (from 1994 to 2021) to
provide an overview of the available methodologies for the synthesis and diverse …

Synthesis, antimicrobial, antioxidant, anti-hemolytic and cytotoxic evaluation of new imidazole-based heterocycles

BF Abdel-Wahab, GEA Awad, FA Badria - European journal of medicinal …, 2011 - Elsevier
In the present work, 1-(5-methyl-2-phenyl-1H-imidazol-4-yl) ethanone 1 was prepared and
used as a precursor for the synthesis of new thiazole, arylidiene and coumarin derivatives …

Synthesis and anti-microbial activity of some 1-substituted amino-4, 6-dimethyl-2-oxo-pyridine-3-carbonitrile derivatives

RE Khidre, AA Abu-Hashem, M El-Shazly - European journal of medicinal …, 2011 - Elsevier
A new series of 1-substituted amino-4, 6-dimethyl-2-oxo-pyridine-3-carbonitrile such as
hydrazide hydrazones 3a-h; ethane-1, 2-diaminopyridine 6; phthalimidopyridines 8a, b; …

Solvent-free microwave-assisted synthesis of E-(1)-(6-benzoyl-3,5-dimethylfuro[3′,2′:4,5]benzo[b]furan-2-yl)-3-(aryl)-2-propen-1-ones and their antibacterial …

D Ashok, K Sudershan, M Khalilullah - Green Chemistry Letters …, 2012 - Taylor & Francis
Abstract A series of E-(1)-(6-benzoyl-3, 5-dimethylfuro [3′, 2′: 4, 5] benzo [b] furan-2-yl)-3-
(aryl)-2-propen-1-ones were synthesized by the Claisen–Schimdt reaction of 2-acetyl-3, 5 …

Synthesis, biological evaluation and molecular dynamic simulations of novel Benzofuran-tetrazole derivatives as potential agents against Alzheimer's disease

P Kushwaha, S Fatima, A Upadhyay, S Gupta… - Bioorganic & Medicinal …, 2019 - Elsevier
A series of novel Benzofuran-tetrazole derivatives were successfully synthesised by
integrating multicomponent Ugi-azide reaction with the molecular hybridization approach …

Pyrrolizine/indolizine-bearing (un) substituted isoindole moiety: design, synthesis, antiproliferative and MDR reversal activities, and in silico studies

AL AbdelSamad, MT El-Saadi, AM Gouda… - RSC …, 2023 - pubs.rsc.org
Two new series of pyrrolizine/indolizine derivative-bearing (un) substituted isoindole moiety
were designed and synthesized. The anticancer potential of the new compounds was …

[PDF][PDF] Pyrazole-3 (4)-carbaldehyde: synthesis, reactions and biological activity.

BF Abdel-Wahab, RE Khidre… - ARKIVOC: Online Journal …, 2011 - researchgate.net
This review deals with synthesis and reactions of pyrazole-3 (4)-carbaldehydes as well as
their biological activity. The data on the methods of synthesis, chemical reactions, and …

Synthesis and molluscicidal evaluation of some new pyrazole, isoxazole, pyridine, pyrimidine, 1, 4-thiazine and 1, 3, 4-thiadiazine derivatives incorporating …

MF El Shehry, RH Swellem, SM Abu-Bakr… - European journal of …, 2010 - Elsevier
Chalcone derivative 3 was synthesized via the base catalyzed Claisen–Schmidt
condensation and was used as a precursor for synthesizing pyrazoline 11, isoxazoline 12 …

Applications of the Vilsmeier reaction in heterocyclic chemistry

IA Abdelhamid, MR Shaaban, AHM Elwahy - Advances in Heterocyclic …, 2022 - Elsevier
Heterocyclic scaffolds exist in a wide range of natural products, dyes, and in diverse drugs.
They constitute important structural units in synthetic pharmaceuticals and agrochemicals …

[PDF][PDF] DABCO-catalyzed green synthesis of thiazole and 1, 3-thiazine derivatives linked to benzofuran

SM Gomha, MG Badrey, WAA Arafa - Heterocycles, 2016 - triggered.edinburgh.clockss.org
An eco-friendly and simple procedure for the reaction of 2-(1-(benzofuran-2-yl) ethylidene)
hydrazinecarbothioamide with arylidenemalononitriles and hydrazonoyl halides catalyzed …