The ability of a eukaryotic cell to resist deformation, to transport intracellular cargo and to
change shape during movement depends on the cytoskeleton, an interconnected network of …

Giant unilamellar vesicles (GUVs) have gained great popularity as mimicries for cellular
membranes. As their sizes are comfortably above the optical resolution limit, and their lipid …

Forces generated by protein polymerization are important for various forms of cellular
motility. Assembling microtubules, for instance, are believed to exert pushing forces on …

Dynamic interplay between the plasma membrane and underlying cytoskeleton is essential
for cellular shape change. Spatial organization of actin filaments, the growth of which …

ABSTRACT Three-dimensional (3D) cell motility underlies essential processes, such as
embryonic development, tissue repair and immune surveillance, and is involved in cancer …

Understanding the behavior of low-dimensional nanomaterials confined in intracellular
vesicles has been limited by the resolution of bioimaging techniques and the complex …

Carbon nanotubes and biological filaments each spontaneously assemble into kinked
helices, rings, and “tennis racket” shapes due to competition between elastic and interfacial …

Microtubules are dynamic protein polymers that continuously switch between elongation
and rapid shrinkage. They have an exceptional bending stiffness that contributes …

A fundamental understanding of cell shaping with confined flexible filaments, including
microtubules, actin filaments, and engineered nanotubes, has been limited by the complex …

Based on rigorous experimental, clinical, and mathematical analysis, the mechanism of
accommodation and presbyopia is elucidated. During accommodation the anterior radial …