Melanoma is a highly aggressive cancer with the poorest prognosis, representing the
deadliest form of skin cancer. Activating mutations in BRAF are the most frequent genetic …

Chemoresistance represents the main obstacle to cancer treatment with both conventional
and targeted therapy. Beyond specific molecular alterations, which can lead to targeted …

Accumulating evidence has indicated that corosolic acid exerts anti‑diabetic, anti‑obesity,
anti‑inflammatory, anti‑hyperlipidemic and anti‑viral effects. More importantly, corosolic acid …

Chemoresistance represents one of the main obstacles in treating several types of cancer,
including bladder and ovarian cancers, and it is characterized by an increase of cellular …

Ethnopharmacological relevance The dried bark of Ailanthus altissima (Mill.) Swingle (BAA),
commonly designated as “Chunpi” in Chinese, is extensively used as a common traditional …

In this report, we synthesized three new iridium (III) complexes:[Ir (piq) 2 (apip)] PF 6 (Ir1,
piq= 1-phenylisoquinoline, apip= 2-aminophenyl-1H-imidazo [4, 5-f][1, 10] …

Marsdenia tenacissima injection, a standard Marsdenia tenacissima extract (MTE), has been
approved as an adjuvant therapeutic agent for various cancers. Our previous study showed …

Ailanthone (AIL) is a major quassinoid extracted from the Chinese medicinal herb, Ailanthus
altissima, which has been reported to exert anti‑proliferative effects on various cancer cells …

Cancer is the second leading cause of death after cardiovascular disease. In 2015,> 8.7
million people died worldwide due to cancer, and by 2030 this figure is expected to increase …

Ailanthone (AIT) is a quassinoid natural product isolated from the worldwide‐distributed
plant Ailanthus altissima. The drug displays multiple pharmacological properties, in …