Homologous regulatory factors are widely present in bacteria, but whether homologous
regulators synergistically or differentially regulate different biological functions remains …

Here we employ a 'systems structural biology'approach to functionally characterize an
unconventional α-glucan metabolic pathway from the food-borne pathogen Listeria …

Bifidobacterial carbohydrate metabolism has been studied in considerable detail for a
variety of both plant-and human-derived glycans, particularly involving the bifidobacterial …

Enterohemorrhagic Escherichia coli (EHEC) O157: H7 are human pathogens responsible
for bloody diarrhea and renal failures. EHEC employ a type 3 secretion system to attach …

In B orrelia burgdorferi (B b), the alternative sigma factor RpoS plays a central role during
Bb's adaptation to ticks and mammals. Previous studies have demonstrated that RpoS is not …

With numerous industrial applications, Paenibacillus polymyxa has been accepted as the
candidate of the cell factory for many secondary metabolites. However, as the regulatory …

ROK-family proteins have been described to act either as sugar kinases or as transcriptional
regulators. Few ROK-family regulators have been characterized so far and most of them are …

Invasive listeriosis is relatively rare, but is one of the deadliest food-borne infections,
affecting pregnant women, their fetuses and newborn infants, the elderly and …

Listeria monocytogenes can cause listeriosis in humans through consumption of
contaminated food and can adapt to and grow under a wide array of physiochemical …

NagC is a transcription factor that represses genes involved in N-acetylglucosamine
catabolism in Escherichia coli. Repression by NagC is relieved by interaction with …