Background Skin being the largest organ of the human body plays a very important role in
the permeation and penetration of the drug. In addition, the transdermal drug delivery …

Amphotericin B (AmB), a broad-spectrum polyene antibiotic in the clinic for more than fifty
years, remains the gold standard in the treatment of life-threatening invasive fungal …

Visceral leishmaniasis or Kala-azar is a vector-borne disease caused by an intracellular
parasite of the genus leishmania. In India, Amphotericin B (AmB) is a first-line medication for …

Leishmaniasis is a group of disease caused by the intracellular protozoan parasite of the
genus Leishmania. Infection by different species of Leishmania results in various host …

Leishmaniasis is a vector-borne zoonotic disease caused by protozoan parasites of the
genus Leishmania, which are responsible for numerous clinical manifestations, such as …

This review examined a collection of studies regarding the molecular properties of some
polyene antibiotic molecules as well as their properties in solution and in particular …

Amphotericin B (AmB), a poorly soluble and toxic antifungal drug, was encapsulated into
polymeric micelles self-assembled from phenylboronic acid-functionalized …

Leishmaniases are neglected diseases caused by infection with Leishmania parasites and
there are currently no prophylactic vaccines. In this study, we designed in silico a synthetic …

Objective The present study aimed to elucidate the cell death mechanism in Leishmania
donovani upon treatment with KalsomeTM10, a new liposomal amphotericin B …

Amphotericin B (AmpB) is active against leishmaniasis, but its use is hampered due to its
high toxicity observed in patients. In this study, a nanoparticles-delivery system for AmpB …