Type 1 diabetes mellitus: retrospect and prospect

TA Addissouky, MMA Ali, IET El Sayed… - Bulletin of the National …, 2024 - Springer
Abstract Background Type 1 diabetes (T1D) is an autoimmune disease leading to
destruction of insulin-producing pancreatic beta cells. Both genetic and environmental …

[HTML][HTML] A Fresh Look at Islet Isolation from Rabbit Pancreases

E Vasilchikova, P Ermakova, A Bogomolova… - International Journal of …, 2024 - mdpi.com
Islet transplantation represents a promising therapeutic approach for diabetes management,
yet the isolation and evaluation of pancreatic islets remain challenging. This study focuses …

[HTML][HTML] Effect of isoproterenol, a β-adrenergic agonist, on the differentiation of insulin-producing pancreatic β cells derived from human pluripotent stem cells

HR Jun, YH Kim, JE Moon, S Jeong, HS Goh… - Experimental Cell …, 2024 - Elsevier
Research on islet replacement through the differentiation of functionally matured insulin-
producing β-like cells for the treatment of diabetes presents a significant challenge. Neural …

The role of fetal pancreatic islet cell transplantation in the treatment of type 2 diabetes mellitus

I Kaibagarova, S Saparbaev, R Aringazina… - Journal of Diabetes & …, 2024 - Springer
Objectives Diabetes mellitus has a negative impact on patients' lives and is a significant
medical and social problem. Due to the high prevalence of diabetes mellitus, shortage of …

Secretome analysis of human and rat pancreatic islets co-cultured with adipose-derived stromal cells reveals a signature with enhanced regenerative capacities

E Pinheiro-Machado, BJ de Haan, MA Engelse… - bioRxiv, 2024 - biorxiv.org
Pancreatic islet transplantation (PIT), a promising treatment for Type 1 Diabetes (T1D),
encounters challenges in the pre-and post-transplantation phases. Co-culturing or co …

Stem cell-based approaches for islet replacement in diabetes

Z Ghezel-Ayagh, Y Tahamtani, B Arjmand… - Regenerative …, 2024 - jrb.ssu.ac.ir
Diabetes is a complex and multifactorial metabolic disease characterized by the
autoimmune‎ destruction of pancreatic beta cells or a combination of peripheral insulin …

[PDF][PDF] AMBULATORIAL

LN Monteiro, TFP Silva - helpsmed.s3.us-east-2.amazonaws …
O uso de cigarros eletrônicos, também conhecidos como e-cigarros ou dispositivos de
vaping, tem crescido de forma exponencial nas últimas décadas, especialmente entre os …

Development of an in Vitro Screening Platform for Research of Type 1 Diabetes Therapies

JM Porter - 2023 - search.proquest.com
Diabetes is a chronic disease wherein the afflicted lose their ability to maintain stable blood
glucose levels. In both type 1 and type 2 diabetes, the peptide signaling molecule insulin is …