Tight junction protein signaling and cancer biology

Z Nehme, N Roehlen, P Dhawan, TF Baumert - Cells, 2023 - mdpi.com
Tight junctions (TJs) are intercellular protein complexes that preserve tissue homeostasis
and integrity through the control of paracellular permeability and cell polarity. Recent …

Bioeffects of moderate-intensity static magnetic fields on cell cultures

L Dini, L Abbro - Micron, 2005 - Elsevier
The interaction of static magnetic fields (SMFs) with living organisms is a rapidly growing
field of investigation. However, despite the increasing number of studies on the effects of the …

Design, synthesis, docking, ADMET studies, and anticancer evaluation of new 3-methylquinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers

MM Alanazi, IH Eissa, NA Alsaif… - Journal of Enzyme …, 2021 - Taylor & Francis
Vascular endothelial growth factor receptor-2 (VEGFR-2) plays a critical role in cancer
angiogenesis. Inhibition of VEGFR-2 activity proved effective suppression of tumour …

The impact of proliferation-migration tradeoffs on phenotypic evolution in cancer

JA Gallaher, JS Brown, ARA Anderson - Scientific reports, 2019 - nature.com
Tumors are not static masses of cells but dynamic ecosystems where cancer cells
experience constant turnover and evolve fitness-enhancing phenotypes. Selection for …

Function and Regulation of AUTS2, a Gene Implicated in Autism and Human Evolution

N Oksenberg, L Stevison, JD Wall, N Ahituv - PLoS genetics, 2013 - journals.plos.org
Nucleotide changes in the AUTS2 locus, some of which affect only noncoding regions, are
associated with autism and other neurological disorders, including attention deficit …

Diosmetin inhibits cell proliferation and promotes apoptosis through STAT3/c-Myc signaling pathway in human osteosarcoma cells

R Ning, G Chen, R Fang, Y Zhang, W Zhao, F Qian - Biological Research, 2021 - Springer
Background Diosmetin is a bioflavonoid compound naturally abundant in citrus fruits. It is
found to perform a variety of activities, while its antitumor property in osteosarcoma, a …

Multi-omics analysis to reveal disorders of cell metabolism and integrin signaling pathways induced by PM2. 5

X Song, J Liu, N Geng, Y Shan, B Zhang, B Zhao… - Journal of Hazardous …, 2022 - Elsevier
Atmospheric fine particle pollution is known to cause many adverse health effects. However,
the potential mechanisms of PM 2.5-induced cytotoxicity still needs further understanding …

Influenza A Virus Replication Induces Cell Cycle Arrest in G0/G1 Phase

Y He, K Xu, B Keiner, J Zhou, V Czudai, T Li… - Journal of …, 2010 - Am Soc Microbiol
Many viruses interact with the host cell division cycle to favor their own growth. In this study,
we examined the ability of influenza A virus to manipulate cell cycle progression. Our results …

Assessment of the in vivo genotoxicity of pendimethalin via mitochondrial bioenergetics and transcriptional profiles during embryogenesis in zebrafish: Implication of …

H Park, JY Lee, W Lim, G Song - Journal of hazardous materials, 2021 - Elsevier
Pendimethalin, an herbicide used to control weeds, acts by inhibiting plant cell division and
mitosis. Several studies have reported the detrimental effects of pendimethalin on non-target …

New thiazol-hydrazono-coumarin hybrids targeting human cervical cancer cells: Synthesis, CDK2 inhibition, QSAR and molecular docking studies

SS Abd El-Karim, YM Syam, AM El Kerdawy… - Bioorganic …, 2019 - Elsevier
Motivated by the potential anticancer activity of both coumarin and 2-aminothiazole nuclei, a
new set of thiazol-2-yl hydrazono-chromen-2-one analogs were efficiently synthesized …