Purpose of review This review describes the pharmacology of each antidepressant class as
it applies to migraine prevention, summarizes the evidence base for each medication, and …

Psychiatric drugs have primacy for off-label prescribing. Among those, selective serotonin
reuptake inhibitors (SSRIs) are highly versatile and, therefore, widely prescribed. Moreover …

This chapter covers antidepressants that fall into the class of serotonin (5-HT) and
norepinephrine (NE) reuptake inhibitors. That is, they bind to the 5-HT and NE transporters …

The first edition of the Italian diagnostic and therapeutic guidelines for primary headaches in
adults was published in J Headache Pain 2 (Suppl. 1): 105–190 (2001). Ten years later, the …

Background This is an updated version of the Cochrane review published in 2005 on
selective serotonin re‐uptake inhibitors (SSRIs) for preventing migraine and tension‐type …

Perimenopause marks a period of increased migraine prevalence in women and many
women also report troublesome vasomotor symptoms. Migraine is affected by fluctuating …

Vertigo, dizziness, and disequilibrium are common symptoms following concussion or mild
traumatic brain injury (mTBI). Dizziness and vertigo may be the result of trauma to the …

Background and objectives The role of serotonin–norepinephrine reuptake inhibitors
(SNRIs) in migraine prophylaxis has not been completely established. Current treatments for …

Depression is a common comorbidity in patients with multiple sclerosis (MS). Those with MS
and concurrent depression have poorer quality of life and are also less likely to be compliant …

Objectives To (1) determine the efficacy of venlafaxine XR for the treatment of pain
(secondary aim) in individuals with spinal cord injury (SCI) enrolled in a randomized …