Idiopathic pulmonary fibrosis (IPF) is a chronic progressive fibrotic interstitial pneumonia
with unknown causes. The incidence rate increases year by year and the prognosis is poor …

Idiopathic pulmonary fibrosis (IPF) is a progressive, and ultimately fatal, chronic interstitial
lung disease characterized by enhanced extracellular matrix deposition. Repetitive alveolar …

Pulmonary fibrosis, particularly idiopathic pulmonary fibrosis, represents a chronic and
progressive disease with high mortality and limited therapeutic options. Excessive …

Pulmonary fibrosis is a chronic lung disease characterized by excessive accumulation of
extracellular matrix (ECM) and remodeling of the lung architecture. Idiopathic pulmonary …

The molecular mechanisms of pulmonary fibrosis are poorly understood, although reactive
oxygen species are thought to have an important role. NRF2 is a transcription factor that …

Cigarette smoking is reported in about one third of adults worldwide. A strong relationship
between cigarette smoke exposure and chronic obstructive pulmonary disease (COPD) as …

The systemic and organ-specific human fibrotic disorders collectively represent one of the
most serious health problems world-wide causing a large proportion of the total world …

Increased lung IL-4 expression in pulmonary fibrosis suggests a potential pathogenetic role
for this cytokine. To dissect this role, bleomycin-induced pulmonary inflammation and …

Progressive pulmonary fibrosis results from a dysfunctional tissue repair response and is
characterized by fibroblast proliferation, activation, and invasion and extracellular matrix …

Silicon dioxide (SiO2) is a mineral compound present in the Earth's crust in two mineral
forms: crystalline and amorphous. Based on epidemiological and/or biological evidence, the …