Since the beginning of the 1990's diverse types of metabolites originating from
polyunsaturated fatty acids, formed under autooxidative conditions were discovered. Known …

Metabolomics, as a part of systems biology, has been widely applied in different fields of life
science by studying the endogenous metabolites. The development and applications of …

Over the past decade, the number of known eicosanoids has expanded immensely and we
have now developed an ultra-performance liquid chromatography–electrospray ionization …

Lipid autacoids derived from n-3/n-6 polyunsaturated fatty acids (PUFA) are some of the
earliest signals triggered by an inflammatory reaction. They are acting also as essential …

Eicosanoids are biologically active lipid mediators, comprising prostaglandins, leukotrienes,
thromboxanes, and lipoxins, involved in several pathophysiological processes relevant to …

Oxylipins are bioactive mediators that play diverse roles in (patho) physiology. We
developed a sensitive and selective ultra-performance liquid chromatography-tandem mass …

Free arachidonic acid is functionally interlinked with different lipid signaling networks
including those involving prostanoid pathways, the endocannabinoid system, N …

Oxylipins are important biological regulators that have received extensive research
attention. Due to the extremely low concentrations, large concentration variations, and high …

Eicosanoids are a large family that derives from arachidonic acid, ie, eicosatetraenoic acid.
Prominent members include prostaglandins, thromboxane and leukotrienes. They are …

Metabolites of non-enzymatic lipid peroxidation of polyunsaturated fatty acids notably
omega-3 and omega-6 fatty acids have become important biomarkers of lipid products …