Pyrazole and its derivatives are considered a pharmacologically important active scaffold
that possesses almost all types of pharmacological activities. The presence of this nucleus in …

Pyrazole, a five membered heteroaromatic ring with two nitrogen atoms is of immense
significance. Presence of this nucleus in the pharmacological agents of diverse therapeutic …

Abstract New crystal,(E)-N'-(4-(dimethylamino) benzylidene)-5-methyl-1H-pyrazole-3-
carbohydrazide (3) has been synthesized and characterized by FT-IR, NMR, ESI-MS and …

Alzheimer's disease (AD) is a multifactorial neurological disorder among elderly people and
combinatorial factors such as genetic, lifestyle, and environmental are involved in onset and …

Alzheimer's Disease (AD) is a progressive neurodegenerative disorder that effects 50 million
people worldwide. In this review, AD pathology and the development of novel therapeutic …

Acetylcholinesterase is an important biochemical enzyme in that it controls acetylcholine-
mediated neuronal transmission in the central nervous system, contains a unique structure …

In this study, a new series of quinazolinone-pyrazole hybrids were designed, synthesized
and screened for their α-glucosidase inhibitory activity. The results of the in vitro screening …

Quinoline analogs are an important class of N-based heterocyclic compounds, which have
received extensive attention because of their use in medicinal chemistry and organic …

Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder. Several hallmarks
such as β-amyloid (Aβ) aggregation underlying amyloid plaque formation, Τ …

In the current scenario of medicinal chemistry, quinoline plays a pivotal role in the design of
new heterocyclic compounds with several pharmacological properties, so the search for new …