Advances and challenges in stroke rehabilitation

CM Stinear, CE Lang, S Zeiler, WD Byblow - The Lancet Neurology, 2020 - thelancet.com
Stroke remains a leading cause of adult disability and the demand for stroke rehabilitation
services is growing. Substantial advances are yet to be made in stroke rehabilitation practice …

[HTML][HTML] Effectiveness of using virtual reality–supported exercise therapy for upper extremity motor rehabilitation in patients with stroke: systematic review and meta …

J Chen, CK Or, T Chen - Journal of medical Internet research, 2022 - jmir.org
Background In recent years, efforts have been made to implement virtual reality (VR) to
support the delivery of poststroke upper extremity motor rehabilitation exercises. Therefore, it …

Intermittent theta-burst stimulation improves motor function by inhibiting neuronal pyroptosis and regulating microglial polarization via TLR4/NFκB/NLRP3 signaling …

L Luo, M Liu, Y Fan, J Zhang, L Liu, Y Li… - Journal of …, 2022 - Springer
Background Neuronal pyroptosis and neuroinflammation with excess microglial activation
are widely involved in the early pathological process of ischemic stroke. Repetitive …

[HTML][HTML] Inflammatory responses after ischemic stroke

JH DeLong, SN Ohashi, KC O'Connor… - Seminars in …, 2022 - Springer
Ischemic stroke generates an immune response that contributes to neuronal loss as well as
tissue repair. This is a complex process involving a range of cell types and effector …

Robot assisted training for the upper limb after stroke (RATULS): a multicentre randomised controlled trial

H Rodgers, H Bosomworth, HI Krebs, F van Wijck… - The Lancet, 2019 - thelancet.com
Background Loss of arm function is a common problem after stroke. Robot-assisted training
might improve arm function and activities of daily living. We compared the clinical …

Encouraging an excitable brain state: mechanisms of brain repair in stroke

MT Joy, ST Carmichael - Nature Reviews Neuroscience, 2021 - nature.com
Stroke induces a plastic state in the brain. This period of enhanced plasticity leads to the
sprouting of new axons, the formation of new synapses and the remapping of sensory-motor …

Standardized measurement of sensorimotor recovery in stroke trials: consensus-based core recommendations from the stroke recovery and rehabilitation roundtable

G Kwakkel, NA Lannin, K Borschmann… - … Journal of Stroke, 2017 - journals.sagepub.com
Finding, testing and demonstrating efficacy of new treatments for stroke recovery is a
multifaceted challenge. We believe that to advance the field, neurorehabilitation trials need …

Precision medicine in stroke: towards personalized outcome predictions using artificial intelligence

AK Bonkhoff, C Grefkes - Brain, 2022 - academic.oup.com
Stroke ranks among the leading causes for morbidity and mortality worldwide. New and
continuously improving treatment options such as thrombolysis and thrombectomy have …

Biomarkers of stroke recovery: consensus-based core recommendations from the stroke recovery and rehabilitation roundtable

LA Boyd, KS Hayward, NS Ward… - … Journal of Stroke, 2017 - journals.sagepub.com
The most difficult clinical questions in stroke rehabilitation are “What is this patient's potential
for recovery?” and “What is the best rehabilitation strategy for this person, given her/his …

[HTML][HTML] Early rehabilitation after stroke: a narrative review

ER Coleman, R Moudgal, K Lang, HI Hyacinth… - Current atherosclerosis …, 2017 - Springer
Abstract Purpose of Review Despite current rehabilitative strategies, stroke remains a
leading cause of disability in the USA. There is a window of enhanced neuroplasticity early …