In general, heterocyclic compounds are a significant source of pharmacologically active
compounds. Among them, the indole scaffold widely distributes in natural products and …

Indoles constitute extensively explored heterocyclic ring systems with wide range of
applications in pathophysiological conditions that is, cancer, microbial and viral infections …

The indole scaffold is one of the most widespread heterocycles in the naturally occurring
and synthetic bioactive compounds including anticancer agents. Due to its biodiversity and …

Antibacterial-resistance speaks to an overall alarm, particularly in regards to the flare-up of
methicillin-resistance Staphylococcus aureus (MRSA), a classic reason for genuine skin and …

Background: Cancer accounts for several deaths each year. There are multiple FDA
approved drugs for cancer treatments. Due to the severe side effects and multiple drug …

Heterocyclic moiety serve as perfect framework on which pharmacophores can be effectively
attached to produce novel drugs. Among various heterocyclic compounds, nitrogen-based …

The one-pot three-component method for the switchable synthesis of 2-methylene-3-
aminoindolines and 2-methyl-3-aminoindoles by reactions of N-(2-formylaryl) sulfonamides …

In this study, we aimed to (i) synthesize new 2-methylindole analogs containing various
amino structures, pyrrolidine, piperidine, morpholine, and substituted phenyl groups through …

Cancer is one of the most prominent causes of death worldwide and tubulin is a crucial
protein of cytoskeleton that maintains essential cellular functions including cell division as …

The broad prospects of trifluoromethylated compounds in materials science, agricultural
chemistry, and pharmaceutical chemistry have stimulated the rapid development of …