Vesicle trafficking and vesicle fusion: mechanisms, biological functions, and their implications for potential disease therapy

L Cui, H Li, Y Xi, Q Hu, H Liu, J Fan, Y Xiang… - Molecular …, 2022 - Springer
Intracellular vesicle trafficking is the fundamental process to maintain the homeostasis of
membrane-enclosed organelles in eukaryotic cells. These organelles transport cargo from …

RNA binding proteins and regulation of mRNA translation in erythropoiesis

KS Moore, M von Lindern - Frontiers in physiology, 2018 - frontiersin.org
Control of gene expression in erythropoiesis has to respond to signals that may emerge from
intracellular processes or environmental factors. Control of mRNA translation allows for …

Shifts in ribosome engagement impact key gene sets in neurodevelopment and ubiquitination in Rett syndrome

DC Rodrigues, M Mufteev, RJ Weatheritt, U Djuric… - Cell reports, 2020 - cell.com
Regulation of translation during human development is poorly understood, and its
dysregulation is associated with Rett syndrome (RTT). To discover shifts in mRNA ribosomal …

Host adaptive mutations in the 2009 H1N1 pandemic influenza A virus PA gene regulate translation efficiency of viral mRNAs via GRSF1

M Lutz, J Schmierer, T Takimoto - Communications Biology, 2022 - nature.com
Avian species are the major natural reservoir from which pandemic influenza A viruses can
be introduced to humans. Avian influenza A virus genes, including the three viral …

Pterostilbene prevents AKT-ERK axis-mediated polymerization of surface fibronectin on suspended lung cancer cells independently of apoptosis and suppresses …

YJ Wang, JF Lin, LH Cheng, WT Chang… - Journal of Hematology & …, 2017 - Springer
Background Polymeric fibronectin (polyFN) assembled on suspended breast cancer cells is
required for metastasis. Conceivably, drugs that target such polyFN may fight against cancer …

[HTML][HTML] Guanine-rich RNA sequence binding factor 1 regulates neuronal ferroptosis after spinal cord injury in rats via the GPX4 signaling pathway

J Wang, J Lu, Y Zhu, Q Huang, Q Gu, S Tian, J Ge… - Brain Research, 2023 - Elsevier
Spinal cord injury (SCI) can trigger multiple forms of neuronal cell death. Among these,
ferroptosis stands out as a particularly important style of cell death due to its iron overload …

GRSF1 antagonizes age-associated hypercoagulability via modulation of fibrinogen mRNA stability

D Liu, C Xu, Z Gong, Y Zhao, Z Fang, X Rao… - Cell Death & …, 2023 - nature.com
Age-associated hypercoagulability is accompanied by the increase of plasma levels of some
coagulation factors including fibrinogen which may contribute to the increased risk of …

Male guanine-rich RNA sequence binding factor 1 knockout mice (Grsf1−/−) gain less body weight during adolescence and adulthood

B Dumoulin, D Heydeck, D Jähn, M Lassé, S Sofi… - Cell & Bioscience, 2022 - Springer
The guanine-rich RNA sequence binding factor 1 (GRSF1) is an RNA-binding protein of the
heterogenous nuclear ribonucleoprotein H/F (hnRNP H/F) family that binds to guanine-rich …

ICP4-induced miR-101 attenuates HSV-1 replication

X Wang, C Diao, X Yang, Z Yang, M Liu, X Li… - Scientific Reports, 2016 - nature.com
Hepes simplex Virus type 1 (HSV-1) is an enveloped DNA virus that can cause lytic and
latent infection. miRNAs post-transcriptionally regulate gene expression and our previous …

Expression regulation, protein chemistry and functional biology of the guanine-rich sequence binding factor 1 (GRSF1)

B Dumoulin, C Ufer, H Kuhn, S Sofi - Journal of Molecular Biology, 2021 - Elsevier
In eukaryotic cells RNA-binding proteins have been implicated in virtually all post-
transcriptional mechanisms of gene expression regulation. Based on the structural features …