Background & Aims Liver biopsies are a critical component of pivotal studies in non-
alcoholic steatohepatitis (NASH), constituting inclusion criteria, risk stratification factors and …

Obesity is a known risk factor for the development of non-alcoholic fatty liver disease
(NAFLD); however, it has been suggested that dietary fat, both amount and composition …

Background Diagnostic tools for liver disease can now include estimation of the grade of
hepatic steatosis (S0 to S3). Controlled attenuation parameter (CAP) is a non-invasive …

Nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (NASH) is associated
with metabolic syndrome and is rapidly increasing globally with the increased prevalence of …

Introduction Late stage clinical trials in non-alcoholic steatohepatitis (NASH) are currently
required by the FDA to use liver biopsy as a primary endpoint. The well-reported limitations …

Non-alcoholic fatty liver disease (NAFLD) and the progressive form of non-alcoholic
steatohepatitis (NASH) are diseases of major importance with a high unmet medical need …

In pathology, tissue samples are assessed using multiple staining techniques to enhance
contrast in unique histologic features. In this paper, we introduce a multimodal CNN-GNN …

BACKGROUND Non-invasive assessment of non-alcoholic steatohepatitis (NASH) is
increasing in desirability due to the invasive nature and costs associated with the current …

Objectives To investigate the use of MR elastography (MRE)–derived mechanical properties
(shear stiffness (| G*|) and loss modulus (G ″)) and MRI-derived fat fraction (FF) to predict …

Background Pathologist evaluation of donor liver biopsies provides information for accepting
or discarding potential donor livers. Due to the urgent nature of the decision process, this is …