Biobased polyurethanes for biomedical applications

S Wendels, L Avérous - Bioactive Materials, 2021 - Elsevier
Polyurethanes (PUs) are a major family of polymers displaying a wide spectrum of physico-
chemical, mechanical and structural properties for a large range of fields. They have shown …

Modeling physiological events in 2D vs. 3D cell culture

K Duval, H Grover, LH Han, Y Mou… - …, 2017 - journals.physiology.org
Cell culture has become an indispensable tool to help uncover fundamental biophysical and
biomolecular mechanisms by which cells assemble into tissues and organs, how these …

Degradation and stabilization of polyurethane elastomers

F Xie, T Zhang, P Bryant, V Kurusingal… - Progress in Polymer …, 2019 - Elsevier
Polyurethane elastomers have a combination of excellent mechanical, physical and
chemical properties along with exceptional biocompatibility. Therefore, these elastomeric …

Biodegradable elastomers for biomedical applications

S Chen, Y Wang, L Yang, C Chu, S Cao, Z Wang… - Progress in Polymer …, 2023 - Elsevier
Synthetic biodegradable elastomers, such as polyesters and polyurethanes have
revolutionized biomedical therapeutic strategies and devices. Driven by innovations in …

Elastomeric biomaterials for tissue engineering

Q Chen, S Liang, GA Thouas - Progress in polymer science, 2013 - Elsevier
Biomaterials play a critical role in engineering of tissue constructs, working as an artificial
extracellular matrix to support regeneration. Because the elastic stretchability is a major …

Rational design of biodegradable thermoplastic polyurethanes for tissue repair

C Xu, Y Hong - Bioactive Materials, 2022 - Elsevier
As a type of elastomeric polymers, non-degradable polyurethanes (PUs) have a long history
of being used in clinics, whereas biodegradable PUs have been developed in recent …

[HTML][HTML] In situ heart valve tissue engineering using a bioresorbable elastomeric implant–From material design to 12 months follow-up in sheep

J Kluin, H Talacua, AIPM Smits, MY Emmert… - Biomaterials, 2017 - Elsevier
The creation of a living heart valve is a much-wanted alternative for current valve prostheses
that suffer from limited durability and thromboembolic complications. Current strategies to …

Biomaterial-driven in situ cardiovascular tissue engineering—a multi-disciplinary perspective

TB Wissing, V Bonito, CVC Bouten… - NPJ Regenerative …, 2017 - nature.com
There is a persistent and growing clinical need for readily-available substitutes for heart
valves and small-diameter blood vessels. In situ tissue engineering is emerging as a …

3D bioprinting of tumor models for cancer research

Y Kang, P Datta, S Shanmughapriya… - ACS Applied Bio …, 2020 - ACS Publications
The exact mechanistic understanding of cancer metastasis continues to be unknown,
although it is a major cause of death worldwide. Along with the tumor mass, the tumor …

Macroporous hydrogel scaffolds for three-dimensional cell culture and tissue engineering

C Fan, DA Wang - Tissue Engineering Part B: Reviews, 2017 - liebertpub.com
Hydrogels have been promising candidate scaffolds for cell delivery and tissue engineering
due to their tissue-like physical properties and capability for homogeneous cell loading …