Abstract Background and Hypothesis Psychotic experiences (PEs) are associated with
increased risk for mental disorders, in particular persistent PEs. PEs therefore might be …

Recent studies have demonstrated substantial phenotypic overlap, notably social
impairment, between autism spectrum disorder (ASD) and schizophrenia. However, the …

BackgroundDuring the last decades, a renewed interest for negative symptoms (NS) was
brought about by the increased awareness that they interfere severely with real-life …

The contribution of the construction sector to the socio-economic development of Ghana
cannot be underestimated. However, these benefits are not without challenges such as …

Studies attempting to deconstruct the heterogeneity of schizophrenia and the attenuated
psychosis syndrome consistently find that negative symptoms are a core dimension that is …

Introduction Negative symptoms in schizophrenia are associated with poor response to
available treatments, poor quality of life, and functional outcome. Therefore, they represent a …

Background Early-onset psychosis (EOP) refers to the development of a first episode of
psychosis before 18 years of age. Individuals at clinical high risk for psychosis (CHR-P) …

Synaptic deficit-induced excitation and inhibition (E/I) imbalance have been implicated in the
pathogenesis of schizophrenia. Using in vivo two-photon microscopy, we examined the …

Aim Youth at CHR for psychosis often demonstrate significant negative symptoms and poor
functioning, though the magnitude and direction of the relationship between the two remains …

Prediction of psychosis is already possible with an excellent prognostic performance based
on clinical assessments. Recent studies show that this accuracy can be further improved by …