Dietary fibre in gastrointestinal health and disease

SK Gill, M Rossi, B Bajka, K Whelan - Nature Reviews Gastroenterology …, 2021 - nature.com
Epidemiological studies have consistently demonstrated the benefits of dietary fibre on
gastrointestinal health through consumption of unrefined whole foods, such as wholegrains …

Anti-inflammatory and immunomodulatory effects of probiotics in gut inflammation: a door to the body

F Cristofori, VN Dargenio, C Dargenio… - Frontiers in …, 2021 - frontiersin.org
Hosting millions of microorganisms, the digestive tract is the primary and most important part
of bacterial colonization. On one side, in cases of opportunistic invasion, the abundant …

Host–microbiota interactions in inflammatory bowel disease

R Caruso, BC Lo, G Núñez - Nature Reviews Immunology, 2020 - nature.com
The mammalian intestine is colonized by trillions of microorganisms that have co-evolved
with the host in a symbiotic relationship. The presence of large numbers of symbionts near …

[HTML][HTML] Gut microbiome: profound implications for diet and disease

RD Hills, BA Pontefract, HR Mishcon, CA Black… - Nutrients, 2019 - mdpi.com
The gut microbiome plays an important role in human health and influences the
development of chronic diseases ranging from metabolic disease to gastrointestinal …

Global burden of irritable bowel syndrome: trends, predictions and risk factors

CJ Black, AC Ford - Nature reviews Gastroenterology & hepatology, 2020 - nature.com
Irritable bowel syndrome (IBS) is one of the most common disorders of gut–brain interaction
worldwide, defined according to patterns of gastrointestinal symptoms as described by the …

Mechanisms, evaluation, and management of chronic constipation

AE Bharucha, BE Lacy - Gastroenterology, 2020 - Elsevier
With a worldwide prevalence of 15%, chronic constipation is one of the most frequent
gastrointestinal diagnoses made in ambulatory medicine clinics, and is a common source …

Systematic review with meta‐analysis: the efficacy of prebiotics, probiotics, synbiotics and antibiotics in irritable bowel syndrome

AC Ford, LA Harris, BE Lacy… - Alimentary …, 2018 - Wiley Online Library
Background Irritable bowel syndrome (IBS) is a chronic functional bowel disorder.
Disturbances in the gastrointestinal microbiome may be involved in its aetiology. Aim To …

The human gut microbiome: from association to modulation

TSB Schmidt, J Raes, P Bork - Cell, 2018 - cell.com
Our understanding of the human gut microbiome continues to evolve at a rapid pace, but
practical application of thisknowledge is still in its infancy. This review discusses the type of …

[HTML][HTML] The microbiome and irritable bowel syndrome–a review on the pathophysiology, current research and future therapy

PP Chong, VK Chin, CY Looi, WF Wong… - Frontiers in …, 2019 - frontiersin.org
Irritable bowel syndrome (IBS) is a functional disorder which affects a large proportion of the
population globally. The precise etiology of IBS is still unknown, although consensus …

Probiotic Bifidobacterium longum NCC3001 reduces depression scores and alters brain activity: a pilot study in patients with irritable bowel syndrome

MI Pinto-Sanchez, GB Hall, K Ghajar, A Nardelli… - Gastroenterology, 2017 - Elsevier
Background & Aims Probiotics can reduce symptoms of irritable bowel syndrome (IBS), but
little is known about their effects on psychiatric comorbidities. We performed a prospective …