Baculovirus and insect cell culture technologies have mostly been limited to research
laboratories for the transient expression of target proteins for drug development purposes …

Commercial vaccines currently available against swine influenza virus (SIV) are inactivated,
adjuvanted, whole virus vaccines, based on H1N1 and/or H3N2 and/or H1N2 SIVs. In …

Influenza viruses pose a significant threat to the public and are a burden on global health
systems,. Each year, influenza vaccines must be rapidly produced to match circulating …

Influenza viruses take a yearly toll on human life despite efforts to contain them with
seasonal vaccines. These viruses evade human immunity through the evolution of variants …

Recent cases of avian influenza H5N1 and the swine-origin 2009 H1N1 have caused a
great concern that a global disaster like the 1918 influenza pandemic may occur again. Viral …

New strains of H1N1 influenza virus have emerged episodically over the last century to
cause human pandemics, notably in 1918 and recently in 2009. Pandemic viruses typically …

ABSTRACT A live attenuated influenza A/Vietnam/1203/2004 (H5N1) vaccine virus (VN04
ca) has receptor binding specificity to α2, 3-linked sialosides (α2, 3SAL), and a single dose …

The baculovirus expression system is a powerful tool for expression of recombinant proteins.
Here we use it to produce correctly folded and glycosylated versions of the influenza A virus …

Recently, a new class of broadly neutralizing anti-influenza virus antibodies that target the
stalk domain of the viral hemagglutinin was discovered. As such, induction, isolation …

Background. H5 DNA priming was previously shown to improve the antibody response to
influenza A (H5N1) monovalent inactivated vaccine (MIV) among individuals for whom there …