Molecular probes, chemosensors, and nanosensors for optical detection of biorelevant molecules and ions in aqueous media and biofluids

J Krämer, R Kang, LM Grimm, L De Cola… - Chemical …, 2022 - ACS Publications
Synthetic molecular probes, chemosensors, and nanosensors used in combination with
innovative assay protocols hold great potential for the development of robust, low-cost, and …

Measuring biomarkers in wastewater as a new source of epidemiological information: Current state and future perspectives

E Gracia-Lor, S Castiglioni, R Bade, F Been… - Environment …, 2017 - Elsevier
The information obtained from the chemical analysis of specific human excretion products
(biomarkers) in urban wastewater can be used to estimate the exposure or consumption of …

Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord

Y Wang, S Springer, M Zhang… - Proceedings of the …, 2015 - National Acad Sciences
Cell-free DNA shed by cancer cells has been shown to be a rich source of putative tumor-
specific biomarkers. Because cell-free DNA from brain and spinal cord tumors cannot …

Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas

Y Wang, S Springer, CL Mulvey, N Silliman… - Science translational …, 2015 - science.org
To explore the potential of tumor-specific DNA as a biomarker for head and neck squamous
cell carcinomas (HNSCC), we queried DNA from saliva or plasma of 93 HNSCC patients …

Urine biomarkers in cancer detection: A systematic review of preanalytical parameters and applied methods

S Jordaens, K Zwaenepoel, W Tjalma… - … Journal of Cancer, 2023 - Wiley Online Library
The aim of this review was to explore the status of urine sampling as a liquid biopsy for
noninvasive cancer research by reviewing used preanalytical parameters and protocols. We …

Electrospun nanofibers for drug delivery and biosensing

C Cleeton, A Keirouz, X Chen… - ACS biomaterials science …, 2019 - ACS Publications
Early diagnosis and efficient treatment are of paramount importance to fighting cancers.
Monitoring the foreign body response of a patient to treatment therapies also plays an …

Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy

SU Springer, CH Chen, MDC Rodriguez Pena, L Li… - Elife, 2018 - elifesciences.org
Current non-invasive approaches for detection of urothelial cancers are suboptimal. We
developed a test to detect urothelial neoplasms using DNA recovered from cells shed into …

The biological complexity of urothelial carcinoma: Insights into carcinogenesis, targets and biomarkers of response to therapeutic approaches

PD Grivas, M Melas, AG Papavassiliou - Seminars in cancer biology, 2015 - Elsevier
Bladder cancer is a major cause of morbidity, mortality and health-related costs. Urothelial
carcinoma is by far the most common histologic type of bladder cancer and may also arise …

Genomic complexity of urothelial bladder cancer revealed in urinary cfDNA

FS Togneri, DG Ward, JM Foster, AJ Devall… - European Journal of …, 2016 - nature.com
Urothelial bladder cancers (UBCs) have heterogeneous clinical characteristics that are
mirrored in their diverse genomic profiles. Genomic profiling of UBCs has the potential to …

The translational potential of microRNAs as biofluid markers of urological tumours

A Fendler, C Stephan, GM Yousef… - Nature Reviews …, 2016 - nature.com
MicroRNAs (miRNAs) are secreted by cells in vesicles, bound in a ribonucleoprotein
complex or as free molecules. These miRNA secretion pathways are dysregulated in cancer …