One of the current challenges in the monitoring of drug nanocarriers lies in the difficulties in
discriminating the carrier-bound signals from the bulk signals of probes. Environment …

Macromolecular therapeutics of biological origin, also known as biologics, have become
one of the fastest-growing classes of drugs for management of a range of chronic and acute …

Background: Localized delivery of antimicrobial agents such as antimicrobial peptides
(AMPs) by a biomaterial should be on-demand. Namely, AMPs should be latent and …

Despite the promise of ribonucleic acid interference therapeutics, the delivery of
oligonucleotides selectively to diseased tissues in the body, and specifically to the cellular …

To combat the increasing risk of infection by pathogenic bacteria, the new generation of
antimicrobial agents is expected to exhibit nonmetabolic killing mechanisms, high potency …

Porous silicon nanoparticles (PSiNPs) have attracted increasing interest as biomedical
probes for drug delivery and imaging. In particular, a set of unique properties including …

Surface engineering of the nanomaterials opens a new era of their biomedical applications.
To date, various kinds of nanoparticles and their surface engineering techniques have been …

Bacterial infections of the respiratory tract cause millions of deaths annually. Several
diseases exist wherein (1) bacterial infection is the main cause of disease (eg, tuberculosis …

Traumatic brain injury (TBI) is a major cause of disability and death among children and
young adults in the United States, yet there are currently no treatments that improve the long …

Surface functionalization of nanoparticles with polyethylene glycol (PEG) has been widely
demonstrated as an anti-opsonization strategy to reduce protein corona formation which is …