The EcoCyc database: reflecting new knowledge about Escherichia coli K-12

IM Keseler, A Mackie, A Santos-Zavaleta… - Nucleic acids …, 2017 - academic.oup.com
EcoCyc (EcoCyc. org) is a freely accessible, comprehensive database that collects and
summarizes experimental data for Escherichia coli K-12, the best-studied bacterial model …

A microbial transporter of the dietary antioxidant ergothioneine

DG Dumitrescu, EM Gordon, Y Kovalyova… - Cell, 2022 - cell.com
Summary Low-molecular-weight (LMW) thiols are small-molecule antioxidants required for
the maintenance of intracellular redox homeostasis. However, many host-associated …

Salt tolerance mechanism of a hydrocarbon-degrading strain: salt tolerance mediated by accumulated betaine in cells

X Hu, D Li, Y Qiao, Q Song, Z Guan, K Qiu… - Journal of hazardous …, 2020 - Elsevier
Rhodococcus sp. HX-2 could degrade diesel oil in the presence of 1%–10% NaCl. The
compatible solute betaine accumulated in cells with increasing NaCl concentration, and this …

The Effect of Proline on the Freeze-Drying Survival Rate of Bifidobacterium longum CCFM 1029 and Its Inherent Mechanism

S Cui, W Zhou, X Tang, Q Zhang, B Yang… - International Journal of …, 2022 - mdpi.com
Amino acids, which are important compatible solutes, play a significant role in probiotic
lyophilization. However, studies on the functions of Bifidobacterium during freeze-drying are …

Osmotic adaptation and compatible solute biosynthesis of phototrophic bacteria as revealed from genome analyses

JF Imhoff, T Rahn, S Künzel, A Keller, SC Neulinger - Microorganisms, 2020 - mdpi.com
Osmotic adaptation and accumulation of compatible solutes is a key process for life at high
osmotic pressure and elevated salt concentrations. Most important solutes that can protect …

Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli

S Jindal, L Yang, PJ Day, DB Kell - BMC microbiology, 2019 - Springer
Background It is widely believed that most xenobiotics cross biomembranes by diffusing
through the phospholipid bilayer, and that the use of protein transporters is an occasional …

Genome-wide analysis of genes involved in efflux function and regulation within Escherichia coli and Salmonella enterica serovar Typhimurium

ER Holden, M Yasir, AK Turner, J Wain… - …, 2023 - microbiologyresearch.org
The incidence of multidrug-resistant bacteria is increasing globally, with efflux pumps being
a fundamental platform limiting drug access and synergizing with other mechanisms of …

De novogenomic analysis ofEnterobacter asburiaeEBRJ12, a plant growth-promoting rhizobacteria isolated from the rhizosphere of Phaseolus vulgarisL

J Saikia, R Kotoky, R Debnath, N Kumar… - Journal of Applied …, 2023 - academic.oup.com
Aim Environmental stresses such as water deficit induced stress are one of the major limiting
factors in crop production. However, some plant growth-promoting rhizobacteria (PGPR) can …

OpuF, a new Bacillus compatible solute ABC transporter with a substrate-binding protein fused to the transmembrane domain

L Teichmann, H Kümmel, B Warmbold… - Applied and …, 2018 - Am Soc Microbiol
The accumulation of compatible solutes is a common defense of bacteria against the
detrimental effects of high osmolarity. Uptake systems for these compounds are …

[HTML][HTML] Stability of ligand-induced protein conformation influences affinity in maltose-binding protein

M van den Noort, M de Boer, B Poolman - Journal of molecular biology, 2021 - Elsevier
Our understanding of what determines ligand affinity of proteins is poor, even with high-
resolution structures available. Both the non-covalent ligand–protein interactions and the …