Transforming growth factor (TGF)-β is a natural and potent growth inhibitor of a variety of cell
types, including epithelial, endothelial, and hematopoietic cells. The ability of TGF-β to …

Mucin expression was analysed, in relation to cell growth, in parental HT-29 cells and in two
populations of mucus-secreting HT-29 cells selected by adaptation to methotrexate (HT29 …

Soy foods have been reported to have protective effects against premenopausal breast
cancer in Asian women. No studies have been reported on potential physiological effects of …

Programmed cell death comprises several subtypes, as revealed by electron microscopy.
Apoptosis or type I programmed cell death is characterized by condensation of cytoplasm …

Escape from negative growth regulation by transforming growth factor β (TGF-β) as a result
of the loss of TGF-β type II receptor (RII) expression has been found to be associated with …

Stress signals activate the SAPK/JNK and p38 MAPK classes of protein kinases, which
mediate cellular responses, including steps in apoptosis and the maturation of some cell …

The role of transforming growth factor (TGF) beta type II receptor in reversing the malignant
phenotype of human breast cancer MCF-7 cells was examined. MCF-7 cells were …

A co-culture model of the two most abundant intestinal epithelial cell types (absorptive and
goblet cells) was developed on permeable supports using the human Caco-2 and HT29-H …

Our previous results have shown that transforming growth factor β (TGFβ) rapidly activates
Ras, as well as both ERKs and SAPKs. In order to address the biological significance of the …

Smad4 (DPC4) is a candidate tumor suppressor gene that has been hypothesized to be
critical for transmitting signals from transforming growth factor (TGF) β and related ligands …