Abstract Rudolph Virchow (1821–1902) recognized inflammation in histological
preparations of coronary arteries and proposed that inflammation plays a causal role in …

Rheumatoid arthritis is a systemic autoimmune disease characterized by excess morbidity
and mortality from cardiovascular disease. Mechanisms linking rheumatoid arthritis and …

Atherothrombosis is no longer considered solely a disorder of lipoprotein accumulation in
the arterial wall. Rather, the initiation and progression of atherosclerotic lesions is currently …

Background Inflammation plays a fundamental role in atherothrombosis. Yet, whether direct
inhibition of inflammation will reduce the occurrence of adverse cardiovascular outcomes is …

The risk of cardiovascular disease is increased in patients with rheumatoid arthritis
compared with the general population owing to the influence of traditional and non …

The elderly rheumatoid arthritis (RA) population consists of both elderly-onset RA that
manifests after the age of 60 and individuals diagnosed with RA early in life who age …

Objective Rheumatoid arthritis (RA) is associated with an increased risk of cardiovascular
disease (CVD), but longitudinal observations are limited and the precise magnitude is …

Dyslipidaemia is commonly observed in patients with active rheumatoid arthritis (RA), with
lower total cholesterol levels as well as lower levels of high-density lipoprotein cholesterol …

Inflammation has been long regarded as a key contributor to atherosclerosis. Inflammatory
cells and soluble mediators play critical roles throughout arterial plaque development and …

Objective Tofacitinib is an oral JAK inhibitor for the treatment of rheumatoid arthritis (RA).
Systemic inflammation is proposed to play a fundamental role in the altered lipid metabolism …