Glucocorticoid (GC) is one of the most prescribed medicines to treat various inflammatory
and autoimmune diseases. However, high doses and long-term use of GCs lead to multiple …

MicroRNAs are small noncoding RNAs that can bind to the target sites in the 3'‐untranslated
region of messenger RNA to regulate posttranscriptional gene expression. Increasing …

Angiogenesis and osteogenesis are tightly coupled during bone modeling and remodeling
processes. Here we reported that bone marrow mesenchymal stem cell (BMSC)-derived …

Non-alcoholic fatty liver disease (NAFLD) is a common cause of chronic liver disease and
ranges from steatosis to steatohepatitis and to liver fibrosis. Lipotoxicity in hepatocytes …

Non-coding RNAs have been found to regulate several developmental processes among
them is osteogenesis. Although these transcripts have several distinct classes, two classes …

MicroRNAs (miRNAs) are a class of short RNA molecules that mediate the regulation of
gene activity through interactions with target mRNAs and subsequent silencing of gene …

Background: Breast cancer with osteoclast-like stromal giant cells (OSGC) is an exceedingly
rare morphological pattern of invasive breast carcinoma. The tumor immune …

Osteogenesis imperfecta (OI) is not curative nowadays. This study tried to unriddle the
therapeutic potential of micro ribonucleic acid-29a (miR-29a) antagonist in treating OI in a …

High serum levels of osteoprotegerin (OPG) are found in patients with obesity, type 2
diabetes, sepsis, or septic shock and are associated with a high mortality rate in stroke. The …

Abstract miRNAs play a vital role in post-transcriptional regulation of gene expression in
osteoblasts and osteoclasts, and the miR-29 family is expressed in both lineages. Using …