Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and fatal scarring lung disease
of unknown etiology, characterized by changes in microRNA expression. Activation of …

Abstract Syndecan 2 (SDC2) belongs to a four‐member family of evolutionary conserved
small type I transmembrane proteoglycans consisting of a protein core to which …

Idiopathic pulmonary fibrosis is a progressive lung disease with complex pathophysiology
and fatal prognosis. Macrophages (MΦ) contribute to the development of lung fibrosis; …

The impact of lipotoxicity on the development of lung fibrosis is unclear. Saturated fatty
acids, such as palmitic acid (PA), activate endoplasmic reticulum (ER) stress, a cellular …

Dysregulated cell-cell communication is a hallmark of many disease phenotypes. Due to
recent advances in single-cell transcriptomics and computational approaches, it is now …

Background Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterised by
myofibroblast proliferation and abnormal extracellular matrix accumulation in the lungs …

Rationale: CD148/PTRJ (receptor-like protein tyrosine phosphatase η) exerts antifibrotic
effects in experimental pulmonary fibrosis via interactions with its ligand syndecan-2; …

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and an irreversible lung
disorder characterized by the accumulation of fibroblasts and myofibroblasts in the …

Radiation-induced pulmonary fibrosis is a severe complication of patients treated with
thoracic irradiation. We have previously shown that syndecan-2 reduces fibrosis by exerting …

Influenza virus causes a heterogeneous respiratory infectious disease ranging from self-
limiting symptoms to non-resolving pathology in the lungs. Worldwide, seasonal influenza …