Metabolomics-centered mining of plant metabolic diversity and function: Past decade and future perspectives

S Shen, C Zhan, C Yang, AR Fernie, J Luo - Molecular Plant, 2023 - cell.com
Plants are natural experts in organic synthesis, being able to generate large numbers of
specific metabolites with widely varying structures that help them adapt to variable survival …

Natural products for drug discovery in the 21st century: innovations for novel drug discovery

NE Thomford, DA Senthebane, A Rowe… - International journal of …, 2018 - mdpi.com
The therapeutic properties of plants have been recognised since time immemorial. Many
pathological conditions have been treated using plant-derived medicines. These medicines …

Polyphenols as antitumor agents targeting key players in cancer-driving signaling pathways

MH Cháirez-Ramírez, KG de la Cruz-López… - Frontiers in …, 2021 - frontiersin.org
Polyphenols constitute an important group of natural products that are traditionally
associated with a wide range of bioactivities. These are usually found in low concentrations …

Rhizosphere microbiome mediates systemic root metabolite exudation by root-to-root signaling

E Korenblum, Y Dong, J Szymanski… - Proceedings of the …, 2020 - National Acad Sciences
Microbial communities associated with roots confer specific functions to their hosts, thereby
modulating plant growth, health, and productivity. Yet, seminal questions remain largely …

From central to specialized metabolism: An overview of some secondary compounds derived from the primary metabolism for their role in conferring nutritional and …

DM Pott, S Osorio, JG Vallarino - Frontiers in plant science, 2019 - frontiersin.org
Fruit flavor and nutritional characteristics are key quality traits and ones of the main factors
influencing consumer preference. Central carbon metabolism, also known as primary …

Medically useful plant terpenoids: biosynthesis, occurrence, and mechanism of action

ME Bergman, B Davis, MA Phillips - Molecules, 2019 - mdpi.com
Specialized plant terpenoids have found fortuitous uses in medicine due to their
evolutionary and biochemical selection for biological activity in animals. However, these …

Demystifying traditional herbal medicine with modern approach

FS Li, JK Weng - Nature plants, 2017 - nature.com
Plants have long been recognized for their therapeutic properties. For centuries, indigenous
cultures around the world have used traditional herbal medicine to treat a myriad of …

[HTML][HTML] The style and substance of plant flavonoid decoration; towards defining both structure and function

S Alseekh, LP de Souza, M Benina, AR Fernie - Phytochemistry, 2020 - Elsevier
Over 8000 different flavonoids have been described and a considerable number of new
flavonoid structures are being elucidated every year. The advent of metabolomics alongside …

Secondary metabolites in plant innate immunity: conserved function of divergent chemicals

A Piasecka, N Jedrzejczak‐Rey, P Bednarek - New Phytologist, 2015 - Wiley Online Library
Plant secondary metabolites carry out numerous functions in interactions between plants
and a broad range of other organisms. Experimental evidence strongly supports the …

Genome-wide prediction of metabolic enzymes, pathways, and gene clusters in plants

P Schläpfer, P Zhang, C Wang, T Kim, M Banf… - Plant …, 2017 - academic.oup.com
Plant metabolism underpins many traits of ecological and agronomic importance. Plants
produce numerous compounds to cope with their environments but the biosynthetic …