[HTML][HTML] Association between Helicobacter pylori eradication and gastric cancer incidence: a systematic review and meta-analysis

YC Lee, TH Chiang, CK Chou, YK Tu, WC Liao, MS Wu… - Gastroenterology, 2016 - Elsevier
Background & Aims Eradication of Helicobacter pylori infection has been reported to reduce
the risk of gastric cancer among asymptomatic individuals in high-risk areas. The magnitude …

Management of Helicobacter pylori infection—the Maastricht IV/Florence consensus report

P Malfertheiner, F Megraud, CA O'Morain, J Atherton… - Gut, 2012 - gut.bmj.com
Management of Helicobacter pylori infection is evolving and in this 4th edition of the
Maastricht consensus report aspects related to the clinical role of H pylori were looked at …

The human microbiome and cancer

SV Rajagopala, S Vashee, LM Oldfield, Y Suzuki… - Cancer Prevention …, 2017 - AACR
Recent scientific advances have significantly contributed to our understanding of the
complex connection between the microbiome and cancer. Our bodies are continuously …

[HTML][HTML] Oxidative stress resulting from Helicobacter pylori infection contributes to gastric carcinogenesis

LD Butcher, G den Hartog, PB Ernst… - Cellular and molecular …, 2017 - Elsevier
Helicobacter pylori is a gram-negative, microaerophilic bacterium that infects the stomach
and can lead to, among other disorders, the development of gastric cancer. The inability of …

Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells

IM Toller, KJ Neelsen, M Steger… - Proceedings of the …, 2011 - National Acad Sciences
The bacterial pathogen Helicobacter pylori chronically infects the human gastric mucosa
and is the leading risk factor for the development of gastric cancer. The molecular …

Collateral damage: insights into bacterial mechanisms that predispose host cells to cancer

A Gagnaire, B Nadel, D Raoult, J Neefjes… - Nature Reviews …, 2017 - nature.com
Infections are estimated to contribute to 20% of all human tumours. Viruses are known to
induce cell transformation, but evidence has also linked bacteria, such as Helicobacter …

[HTML][HTML] A systematic review and meta-analysis of the role of Helicobacter pylori eradication in preventing gastric cancer

T Rokkas, A Rokka, P Portincasa - Annals of Gastroenterology, 2017 - ncbi.nlm.nih.gov
Background Increasing evidence has suggested that Helicobacter pylori (H. pylori)
eradication might prevent the development of gastric cancer (GC). This systematic review …

Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancer

A Mangerich, CG Knutson, NM Parry… - Proceedings of the …, 2012 - National Acad Sciences
Helicobacter hepaticus-infected Rag 2-/-mice emulate many aspects of human inflammatory
bowel disease, including the development of colitis and colon cancer. To elucidate …

Nature meets nurture: molecular genetics of gastric cancer

AN Milne, F Carneiro, C O'morain, GJA Offerhaus - Human genetics, 2009 - Springer
The immensity of genes and molecules implicated in gastric carcinogenesis is
overwhelming and the relevant importance of some of these molecules is too often unclear …

Epigenetic impact of infection on carcinogenesis: mechanisms and applications

N Hattori, T Ushijima - Genome medicine, 2016 - Springer
Viral and bacterial infections are involved in the development of human cancers, such as
liver, nasopharyngeal, cervical, head and neck, and gastric cancers. Aberrant DNA …