Sesquiterpene lactones are a large group of natural compounds, found primarily in plants of
Asteraceae family, with over 5000 structures reported to date. Within this family, genus …

Introduction: With continual focus on oral drug delivery systems (ODDS), the role of freeze-
drying becomes increasingly valuable. While freeze-drying is fundamentally a desiccation …

The pharmaceutical application of artemether (ARM) as an anticancer natural agent is
hampered due to its poor solubility and bioavailability. In the present study, ARM was …

The objective of this study was to improve the dissolution and solubility of dexibuprofen
(DEX) using hydroxypropyl beta cyclodextrin (HPβCD) inclusion complexes and also to …

Nanoparticles (NPs) have long gained significant interest for their use in various drug
formulations in order to increase bioavailability, prolong drug release, and decrease side …

Rivastigmine hydrogen tartrate (RIV-HT) is given orally for Alzheimer's disease. However,
oral therapy shows low brain bioavailability, short half-life and gastrointestinal-mediated …

Artemether, an artemisinin derivative, is used in the management of life-threatening severe
malaria. This study aimed to develop an intravenous dosage form of artemether using …

The solvent-shift strategy was used to identify appropriate polymers that inhibit humidity-
induced solid-state crystallization of amorphous solid dispersions (ASDs). Lacidipine with …

As artemisinin combination therapies (ACTs) are compromised by resistance, we are
evaluating triple combination therapies (TACTs) comprising an amino-artemisinin, a redox …

Cyclodextrins are cyclic oligosaccharides constituted by glucopyranose units linked by-(1, 4)
bonds that show a characteristic donut shape with a hydrophobic cavity and a hydrophilic …