Immune-related adverse events of checkpoint inhibitors

M Ramos-Casals, JR Brahmer, MK Callahan… - Nature reviews Disease …, 2020 - nature.com
Cancer immunotherapies have changed the landscape of cancer treatment during the past
few decades. Among them, immune checkpoint inhibitors, which target PD-1, PD-L1 and …

Neurologic complications of immune checkpoint inhibitors

AM Haugh, JC Probasco… - Expert opinion on drug …, 2020 - Taylor & Francis
Introduction: Immune checkpoint inhibitors (ICI) are associated with a wide spectrum of
neurologic immune-related adverse events (irAEs) including meningo-encephalitis …

Neurological outcomes in immune checkpoint inhibitor-related neurotoxicity

A Farina, C Birzu, MH Elsensohn, A Picca… - Brain …, 2023 - academic.oup.com
While the spectrum of neurological immune checkpoint inhibitor-related adverse events is
expanding, patients' outcomes are not well documented. This study aimed to assess …

Neuroimmunological adverse events associated with immune checkpoint inhibitor: a retrospective, pharmacovigilance study using FAERS database

T Mikami, B Liaw, M Asada, T Niimura… - Journal of neuro …, 2021 - Springer
Purpose To investigate the characteristics and risk factors for neurologic adverse events
(AEs) induced by immune checkpoint inhibitors (ICIs). Methods An observational …

Toxicity spectrum of immunotherapy in advanced lung cancer: a safety analysis from clinical trials and a pharmacovigilance system

YD Yan, Y Zhao, C Zhang, J Fu, YJ Su, XL Cui… - …, 2022 - thelancet.com
Background With the increased use of immune checkpoint inhibitors (ICIs) in advanced lung
cancer, adverse events (AEs), particularly immune-related AEs (irAEs), have garnered …

[HTML][HTML] Neurological complications of cancer immunotherapy

P Roth, S Winklhofer, AMS Müller, R Dummer… - Cancer Treatment …, 2021 - Elsevier
Immunotherapy has emerged as a powerful therapeutic approach in many areas of clinical
oncology and hematology. The approval of ipilimumab, a monoclonal antibody targeting the …

[HTML][HTML] Facial nerve palsy following the administration of COVID-19 mRNA vaccines: analysis of a self-reporting database

K Sato, T Mano, Y Niimi, T Toda, A Iwata… - International Journal of …, 2021 - Elsevier
Objectives: Facial nerve palsy (or Bell's palsy) has occasionally been reported following the
administration of coronavirus disease 2019 (COVID-19) mRNA vaccines (BNT162b2 and …

Neurologic toxicity of immune checkpoint inhibitors: a review of literature

V Albarrán, J Chamorro, DI Rosero… - Frontiers in …, 2022 - frontiersin.org
Immune checkpoint inhibitors have entailed a change of paradigm in the management of
multiple malignant diseases and are acquiring a key role in an increasing number of clinical …

Implication of the gut microbiome and microbial-derived metabolites in immune-related adverse events: emergence of novel biomarkers for cancer immunotherapy

D Dora, SMZ Bokhari, K Aloss, P Takacs… - International journal of …, 2023 - mdpi.com
Immune checkpoint inhibitors (ICIs) have changed how we think about tumor management.
Combinations of anti-programmed death ligand-1 (PD-L1) immunotherapy have become the …

Biomarkers associated with immune-related adverse events under checkpoint inhibitors in metastatic melanoma

M Wölffer, F Battke, M Schulze, M Feldhahn, L Flatz… - Cancers, 2022 - mdpi.com
Simple Summary Our aim was to check for possible associations between clinical
parameters or NGS-based genetic alterations and the occurrence of immune-related …