Cellular actin networks exhibit a wide range of sizes, shapes, and architectures tailored to
their biological roles. Once assembled, these filamentous networks are either maintained in …

Actin is among the most abundant proteins in eukaryotic cells and assembles into dynamic
filamentous networks regulated by many actin binding proteins. The actin cytoskeleton must …

Atherosclerosis is a chronic inflammatory disease and the pathological basis of many fatal
cardiovascular diseases. Macrophages, the main inflammatory cells in atherosclerotic …

Cellular form and function are controlled by the assembly and stability of actin cytoskeletal
structures—but disassembling/pruning these structures is equally essential for the plasticity …

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease caused by
more than sixty genes identified through classic linkage analysis and new sequencing …

Actin and its dynamic structural remodelings are involved in multiple cellular functions,
including maintaining cell shape and integrity, cytokinesis, motility, navigation, and muscle …

Aqueous soft matter, including supramolecular hydrogels capable of exhibiting stimuli–
responsive macroscopic phase transitions, has attracted increasing attention for the …

Background Thymus is the most crucial organ connecting immunity and aging. The
progressive senescence of thymic epithelial cells (TECs) leads to the involution of thymus …

Directed outgrowth of axons is fundamental for the establishment of neuronal networks.
Axon outgrowth is guided by growth cones, highly motile structures enriched in filamentous …

Abstract Background Molecule interacting with CasL-like protein 2 (MICALL2) is believed to
regulate cytoskeleton dynamics, tight junction formation, and neurite outgrowth. However, its …