DNA in extracellular vesicles: biological and clinical aspects

J Elzanowska, C Semira, B Costa‐Silva - Molecular Oncology, 2021 - Wiley Online Library
The study of extracellular vesicles (EVs), especially in the liquid biopsy field, has rapidly
evolved in recent years. However, most EV studies have focused on RNA or protein content …

The cytosolic DNA-sensing cGAS-STING pathway in liver diseases

Z Wang, N Chen, Z Li, G Xu, X Zhan, J Tang… - Frontiers in Cell and …, 2021 - frontiersin.org
Inflammation is regulated by the host and is a protective response activated by the
evolutionarily conserved immune system in response to harmful stimuli, such as dead cells …

[HTML][HTML] Identification of small GTPases that phosphorylate IRF3 through TBK1 activation using an active mutant library screen

JH Yu, EY Moon, J Kim, JH Koo - Biomolecules & Therapeutics, 2023 - ncbi.nlm.nih.gov
Abstract Interferon regulatory factor 3 (IRF3) integrates both immunological and non-
immunological inputs to control cell survival and death. Small GTPases are versatile …

Nucleic Acid-Induced Signaling in Chronic Viral Liver Disease

AA Roca Suarez, B Testoni, TF Baumert… - Frontiers in …, 2021 - frontiersin.org
A hallmark for the development and progression of chronic liver diseases is the persistent
dysregulation of signaling pathways related to inflammatory responses, which eventually …

The dual function of cGAS-STING signaling axis in liver diseases

X Li, J Qu, Y Zhang, R Liu - Acta Pharmacologica Sinica, 2024 - nature.com
Numerous liver diseases, such as nonalcoholic fatty liver disease, hepatitis, hepatocellular
carcinoma, and hepatic ischemia-reperfusion injury, have been increasingly prevalent …

TLR3 promotes hepatocyte proliferation after partial hepatectomy by stimulating uPA expression and the release of tissue‐bound HGF

C Stöß, M Laschinger, B Wang, M Lu… - The FASEB …, 2020 - Wiley Online Library
TLR3 is implicated in anti‐viral immune responses, but may also act as a sensor of tissue
damage in the absence of infection. Here, we provide evidence for an essential role of TLR3 …

超声引导下腹横肌平面阻滞联合舒芬太尼, 右美托咪定镇痛对肝部分切除术后患者疼痛因子, 应激反应和细胞免疫功能的影响.

李瑾, 李珊珊, 白磊, 张蕾… - Progress in Modern …, 2022 - search.ebscohost.com
摘要目的: 探讨超声引导下腹横肌平面阻滞(TAPB) 联合舒芬太尼, 右美托咪定镇痛对肝部分切除
术后患者疼痛因子, 应激反应和细胞免疫功能的影响. 方法: 选择我院2020 年4 月~ 2021 年8 …

Nucleic Acid-Induced Signaling in Chronic Viral Liver Disease

N Laguette - Nucleic Acid-Associated Inflammation, 2021 - books.google.com
A hallmark for the development and progression of chronic liver diseases is the persistent
dysregulation of signaling pathways related to inflammatory responses, which eventually …

[引用][C] Реализация репликативного потенциала печени после частичной гепатэктомии на фоне суперинвазионного описторхоза

СД Лазарев, ВГ Бычков, СМ Пантелеев… - … IV Всероссийской научно …, 2019