Differential contributions of cardiac, coronary and pulmonary artery vagal mechanoreceptors to reflex control of the circulation

JP Moore, LL Simpson… - The Journal of physiology, 2022 - Wiley Online Library
Distinct populations of stretch‐sensitive mechanoreceptors attached to myelinated vagal
afferents are found in the heart and adjoining coronary and pulmonary circulations …

A change of heart: Mechanisms of cardiac adaptation to acute and chronic hypoxia

AM Williams, BD Levine… - The Journal of …, 2022 - Wiley Online Library
Over the last 100 years, high‐altitude researchers have amassed a comprehensive
understanding of the global cardiac responses to acute, prolonged and lifelong hypoxia …

The potential role of the carotid body in COVID-19

A Porzionato, A Emmi, E Stocco… - … of Physiology-Lung …, 2020 - journals.physiology.org
The carotid body (CB) plays a contributory role in the pathogenesis of various respiratory,
cardiovascular, renal, and metabolic diseases through reflex changes in ventilation and …

The effect of hypoxemia on muscle sympathetic nerve activity and cardiovascular function: a systematic review and meta-analysis

MM Tymko, D Young, D Vergel… - American Journal …, 2023 - journals.physiology.org
We conducted a systematic review and meta-analysis to determine the effect of acute
poikilocapnic, high-altitude, and acute isocapnia hypoxemia on muscle sympathetic nerve …

Highs and lows of sympathetic neurocardiovascular transduction: influence of altitude acclimatization and adaptation

LF Berthelsen, GM Fraser… - American Journal …, 2020 - journals.physiology.org
High-altitude (> 2,500 m) exposure results in increased muscle sympathetic nervous activity
(MSNA) in acclimatizing lowlanders. However, little is known about how altitude affects …

The 2018 global research expedition on altitude related chronic health (Global REACH) to Cerro de Pasco, Peru: an experimental overview

MM Tymko, RL Hoiland, JC Tremblay… - Experimental …, 2021 - Wiley Online Library
New Findings What is the central question of this study? Herein, a methodological overview
of our research team's (Global REACH) latest high altitude research expedition to Peru is …

Sympathetic transduction of blood pressure during graded lower body negative pressure in young healthy adults

M Nardone, C Katerberg, AL Teixeira… - American Journal …, 2022 - journals.physiology.org
Sympathetic transduction of blood pressure (BP) is correlated negatively with resting muscle
sympathetic nerve activity (MSNA) in cross-sectional data, but the acute effects of increasing …

Mechanisms underpinning sympathoexcitation in hypoxia

LL Simpson, M Stembridge… - The Journal of …, 2024 - Wiley Online Library
Sympathoexcitation is a hallmark of hypoxic exposure, occurring acutely, as well as
persisting in acclimatised lowland populations and with generational exposure in highland …

[图书][B] Ward, milledge and west's high altitude medicine and physiology

AM Luks, PN Ainslie, JS Lawley, RC Roach… - 2021 - taylorfrancis.com
This pre-eminent work has developed over six editions in response to man's attempts to
climb higher and higher unaided, and to spend more time at altitude for both work and …

A sympathetic view of blood pressure control at high altitude: new insights from microneurographic studies

LL Simpson, CD Steinback… - Experimental …, 2021 - Wiley Online Library
New Findings What is the topic of the review? Sympathoexcitation and sympathetic control
of blood pressure at high altitude. What advances does it highlight? Sustained …