Real-time intrafraction motion monitoring in external beam radiotherapy

J Bertholet, A Knopf, B Eiben… - Physics in medicine …, 2019 - iopscience.iop.org
Radiotherapy (RT) aims to deliver a spatially conformal dose of radiation to tumours while
maximizing the dose sparing to healthy tissues. However, the internal patient anatomy is …

MR-guided proton therapy: a review and a preview

A Hoffmann, B Oborn, M Moteabbed, S Yan… - Radiation …, 2020 - Springer
Background The targeting accuracy of proton therapy (PT) for moving soft-tissue tumours is
expected to greatly improve by real-time magnetic resonance imaging (MRI) guidance. The …

The TOPAS tool for particle simulation, a Monte Carlo simulation tool for physics, biology and clinical research

B Faddegon, J Ramos-Méndez, J Schuemann… - Physica Medica, 2020 - Elsevier
Purpose This paper covers recent developments and applications of the TOPAS TOol for
PArticle Simulation and presents the approaches used to disseminate TOPAS. Materials and …

The future of image-guided radiotherapy will be MR guided

JM Pollard, Z Wen, R Sadagopan… - The British journal of …, 2017 - academic.oup.com
Advances in image-guided radiotherapy (RT) have allowed for dose escalation and more
precise radiation treatment delivery. Each decade brings new imaging technologies to help …

Future of medical physics: real‐time MRI‐guided proton therapy

BM Oborn, S Dowdell, PE Metcalfe, S Crozier… - Medical …, 2017 - Wiley Online Library
With the recent clinical implementation of real‐time MRI‐guided x‐ray beam therapy
(MRXT), attention is turning to the concept of combining real‐time MRI guidance with proton …

MRI-guidance for motion management in external beam radiotherapy: current status and future challenges

C Paganelli, B Whelan, M Peroni… - Physics in Medicine …, 2018 - iopscience.iop.org
High precision conformal radiotherapy requires sophisticated imaging techniques to aid in
target localisation for planning and treatment, particularly when organ motion due to …

Current state and future applications of radiological image guidance for particle therapy

G Landry, C Hua - Medical Physics, 2018 - Wiley Online Library
In this review paper, we first give a short overview of radiological image guidance in photon
radiotherapy, placing emphasis on the fact that linac based radiotherapy has outpaced …

Integrating a low-field open MR scanner with a static proton research beam line: proof of concept

SM Schellhammer, AL Hoffmann, S Gantz… - Physics in Medicine …, 2018 - iopscience.iop.org
On-line image guidance using magnetic resonance (MR) imaging is expected to improve the
targeting accuracy of proton therapy. However, to date no combined system exists. In this …

Feasibility of MRI‐only treatment planning for proton therapy in brain and prostate cancers: dose calculation accuracy in substitute CT images

L Koivula, L Wee, J Korhonen - Medical Physics, 2016 - Wiley Online Library
Purpose: Magnetic resonance imaging (MRI) is increasingly used for radiotherapy target
delineation, image guidance, and treatment response monitoring. Recent studies have …

Motion management in particle therapy

S Mori, AC Knopf, K Umegaki - Medical Physics, 2018 - Wiley Online Library
In this review article, we introduced the importance of “motion management” in advanced
particle therapy. Several publications have reported that organ motion causes dose …