Polycystic ovary syndrome (PCOS) is a highly complex endocrine disorder, characterized by
hyperandrogenemia, menstrual irregularities and polycystic ovaries. A strong genetic …

Asthma and allergic diseases are complex conditions caused by a combination of genetic
and environmental factors. More than 100 genes have been associated with asthma and …

The objective of this review is to focus on putative modified epithelial functions related to
allergy. The dysregulation of the epithelial barrier might result in the allergen uptake, which …

Allergic rhinitis and asthma are common chronic inflammatory diseases of the nasal mucus
membranes and the upper airways with a high prevalence in Western countries. In addition …

Oxidative stress resulting from an increased amount of reactive oxygen species and an
imbalance between oxidants and antioxidants plays an important role in the pathogenesis of …

Background Asthma exacerbations are the commonest cause of medical admissions in
childhood. These have a significant effect on quality of life and are a major financial burden …

Background: Evidence suggests that higher levels of vitamin D and calcium are associated
with greater lung function and that vitamin D is inversely associated with atopic sensitisation …

Background Before the advent of genome-wide association studies (GWAS), ADAM33,
ADRB2, CD14, MS4A2 (alias FCER1B), IL13, IL4, IL4R, and TNF constituted the most …

To cite this article: Diesner SC, Förster‐Waldl E, Olivera A, Pollak A, Jensen‐Jarolim E,
Untersmayr E. Perspectives on immunomodulation early in life. Pediatr Allergy Immunol …

Résumé La dermatite atopique est une maladie hétérogène associée à une inflammation
chronique de la peau qui affecte 15 à 30% des enfants. Les études de cohorte néonatales …