Lung cancer is the leading cause of cancer death worldwide, accounting for more deaths
than breast, prostate and colon cancer combined. While treatment decisions are determined …

Lung cancer is the leading cause of cancer-related death in men and women in the United
States, accounting for approximately 28% of total cancer deaths in 2010 despite comprising …

Lung cancer, which has a low survival rate, is a leading cause of cancer-associated mortality
worldwide. Smoking and air pollution are the major causes of lung cancer; however …

Lung cancer is a major cause of death in the United States and other countries. The risk of
lung cancer is greatly increased by cigarette smoking and by certain occupational …

Lung cancer is the leading cause of cancer mortality worldwide, yet there exists a limited
view of the genetic lesions driving this disease. In this study, an integrated high-resolution …

We used spectral karyotyping to provide a detailed analysis of karyotypic aberrations in the
diverse group of cancer cell lines established by the National Cancer Institute for the …

Identifying specific somatic mutations that drive tumor growth has transformed the treatment
of lung cancer. For example, cancers with sensitizing epidermal growth factor receptor …

Disruption of the histone modification patterns is one of the most common features of human
tumors. However, few genetic alterations in the histone modifier genes have been described …

Annexin A2 (ANXA2) orchestrates multiple biologic processes and clinical associations,
especially in cancer progression. The structure of ANXA2 affects its cellular localization and …

Introduction Recent clinical success of epidermal growth factor (EGFR)-tyrosine kinase
inhibitors (TKIs) in non-small cell lung cancer (NSCLC) have raised hopes that targeting …