[HTML][HTML] Hippocampal dysfunction in the pathophysiology of schizophrenia: a selective review and hypothesis for early detection and intervention
Scientists have long sought to characterize the pathophysiologic basis of schizophrenia and
develop biomarkers that could identify the illness. Extensive postmortem and in vivo …
develop biomarkers that could identify the illness. Extensive postmortem and in vivo …
Effects of stress throughout the lifespan on the brain, behaviour and cognition
SJ Lupien, BS McEwen, MR Gunnar… - Nature reviews …, 2009 - nature.com
Chronic exposure to stress hormones, whether it occurs during the prenatal period, infancy,
childhood, adolescence, adulthood or aging, has an impact on brain structures involved in …
childhood, adolescence, adulthood or aging, has an impact on brain structures involved in …
A large annotated medical image dataset for the development and evaluation of segmentation algorithms
Semantic segmentation of medical images aims to associate a pixel with a label in a medical
image without human initialization. The success of semantic segmentation algorithms is …
image without human initialization. The success of semantic segmentation algorithms is …
[HTML][HTML] Human hippocampal neurogenesis persists in aged adults and Alzheimer's disease patients
Whether hippocampal neurogenesis persists throughout life in the human brain is not fully
resolved. Here, we demonstrate that hippocampal neurogenesis is persistent through the …
resolved. Here, we demonstrate that hippocampal neurogenesis is persistent through the …
Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions
Although the fact that genetic predisposition and environmental exposures interact to shape
development and function of the human brain and, ultimately, the risk of psychiatric …
development and function of the human brain and, ultimately, the risk of psychiatric …
Maternal cortisol over the course of pregnancy and subsequent child amygdala and hippocampus volumes and affective problems
Stress-related variation in the intrauterine milieu may impact brain development and
emergent function, with long-term implications in terms of susceptibility for affective …
emergent function, with long-term implications in terms of susceptibility for affective …
The structural basis of inter-individual differences in human behaviour and cognition
Inter-individual variability in perception, thought and action is frequently treated as a source
of'noise'in scientific investigations of the neural mechanisms that underlie these processes …
of'noise'in scientific investigations of the neural mechanisms that underlie these processes …
Patch-based segmentation using expert priors: Application to hippocampus and ventricle segmentation
Quantitative magnetic resonance analysis often requires accurate, robust, and reliable
automatic extraction of anatomical structures. Recently, template-warping methods …
automatic extraction of anatomical structures. Recently, template-warping methods …
Multi-atlas segmentation of the whole hippocampus and subfields using multiple automatically generated templates
Introduction Advances in image segmentation of magnetic resonance images (MRI) have
demonstrated that multi-atlas approaches improve segmentation over regular atlas-based …
demonstrated that multi-atlas approaches improve segmentation over regular atlas-based …
Quantitative comparison of 21 protocols for labeling hippocampal subfields and parahippocampal subregions in in vivo MRI: towards a harmonized segmentation …
PA Yushkevich, RSC Amaral, JC Augustinack… - Neuroimage, 2015 - Elsevier
Objective An increasing number of human in vivo magnetic resonance imaging (MRI)
studies have focused on examining the structure and function of the subfields of the …
studies have focused on examining the structure and function of the subfields of the …