Mixotrophic cultivation of microalgae: an alternative to produce high-value metabolites

T Castillo, D Ramos, T García-Beltrán… - Biochemical …, 2021 - Elsevier
Microalgae are important sources of biotechnological products, including pigments, lipids,
polyunsaturated fatty acids, polysaccharides, vitamins, and other bioactive compounds …

Diatom molecular research comes of age: model species for studying phytoplankton biology and diversity

A Falciatore, M Jaubert, JP Bouly, B Bailleul… - The Plant …, 2020 - academic.oup.com
Diatoms are the world's most diverse group of algae, comprising at least 100,000 species.
Contributing~ 20% of annual global carbon fixation, they underpin major aquatic food webs …

A critical review of genome editing and synthetic biology applications in metabolic engineering of microalgae and cyanobacteria

IS Ng, BB Keskin, SI Tan - Biotechnology Journal, 2020 - Wiley Online Library
Being the green gold of the future, microalgae and cyanobacteria have recently attracted
considerable interest worldwide, for their metabolites such as lipids, protein, pigments, and …

Investigating mixotrophic metabolism in the model diatom Phaeodactylum tricornutum

V Villanova, AE Fortunato, D Singh… - … of the Royal …, 2017 - royalsocietypublishing.org
Diatoms are prominent marine microalgae, interesting not only from an ecological point of
view, but also for their possible use in biotechnology applications. They can be cultivated in …

The effects of phosphorus limitation on carbon metabolism in diatoms

T Brembu, A Mühlroth, L Alipanah… - … Transactions of the …, 2017 - royalsocietypublishing.org
Phosphorus is an essential element for life, serving as an integral component of nucleic
acids, lipids and a diverse range of other metabolites. Concentrations of bioavailable …

Integrated biomolecular and bioprocess engineering strategies for enhancing the lipid yield from microalgae

B Behera, Y Unpaprom, R Ramaraj, GP Maniam… - … and Sustainable Energy …, 2021 - Elsevier
Algal biofuels have received wide attention in recent years for its potential to reduce the
dependence on conventional fossil fuels. Despite the portrayed advantages of high growth …

Orchestration of transcriptome, proteome and metabolome in the diatom Phaeodactylum tricornutum during nitrogen limitation

IM Remmers, S D'Adamo, DE Martens, RCH de Vos… - Algal research, 2018 - Elsevier
Nitrogen deprivation increases the triacylglycerol (TAG) content in microalgae but also
severely decreases the growth rate. Most approaches that attempted to increase TAG …

Transcriptional orchestration of the global cellular response of a model pennate diatom to diel light cycling under iron limitation

SR Smith, JTF Gillard, AB Kustka, JP McCrow… - PLoS …, 2016 - journals.plos.org
Environmental fluctuations affect distribution, growth and abundance of diatoms in nature,
with iron (Fe) availability playing a central role. Studies on the response of diatoms to low Fe …

Current state and applications of microbial genome-scale metabolic models

WJ Kim, HU Kim, SY Lee - Current Opinion in Systems Biology, 2017 - Elsevier
Genome-scale metabolic models (GEMs) are valuable in describing an organism's entire
metabolism using genomic information and have made huge impact on systems biology and …

Genome-scale model reveals metabolic basis of biomass partitioning in a model diatom

J Levering, J Broddrick, CL Dupont, G Peers, K Beeri… - PloS one, 2016 - journals.plos.org
Diatoms are eukaryotic microalgae that contain genes from various sources, including
bacteria and the secondary endosymbiotic host. Due to this unique combination of genes …