Background The inability to have children affects 10% to 15% of couples worldwide. A male
factor is estimated to account for up to half of the infertility cases with between 25% to 87% of …

Background Sperm chromatin integrity is essential for normal embryo development and
pregnancy outcome. Sperm DNA fragmentation (SDF) testing constitutes a diagnostic tool to …

Objective To evaluate the effect of varicocelectomy on sperm deoxyribonucleic acid
fragmentation (SDF) rates in infertile men with clinical varicocele. Design Systematic review …

Purpose Seminal oxidative stress (OS) is a recognized factor potentially associated with
male infertility, but the efficacy of antioxidant (AOX) therapy is controversial and there is no …

Varicocele, the leading cause of male infertility, can impair sperm quality and fertility via
various oxidative stress mechanisms. An imbalance between excessive reactive oxygen …

It is widely accepted that oxidative stress plays an important role in the pathophysiology of
male infertility and that antioxidants could have a significant role in the treatment of male …

Oxidative stress is a condition due to an imbalance between the concentrations of oxidants
and antioxidants, and it is a well-recognized contributor in several male infertility conditions …

Excessive oxidation and antioxidant imbalance resulting from several conditions may cause
sperm DNA damage, which, in turn, affect male fertility, both natural and assisted. Sperm …

STUDY QUESTION What are the primary outcomes and outcome measures used in
randomized controlled trials (RCTs) evaluating potential treatments for male infertility in the …

The inability to become pregnant for at least 1 year despite regular unprotected intercourse
may indicate infertility of one or both partners. This problem affects approximately 10–20% of …