Plasma membrane integrity is essential for cellular homeostasis. In vivo, cells experience
plasma membrane damage from a multitude of stressors in the extra-and intra-cellular …

Significance: Levels of platelet noncoding RNAs (ncRNAs) are altered by disease, and
ncRNAs may exert functions inside and outside of platelets. Their role in physiologic …

Image-based patient-specific modelling of hemodynamics are gaining increased popularity
as a diagnosis and outcome prediction solution for a variety of cardiovascular diseases …

Hemolysis usually happens instantly when red blood cells (RBCs) rupture under a high
shear stress. However, it is also found to happen gradually in the extracorporeal membrane …

The durability of the current polymeric heart valves remains to be improved, which has
proven to be highly dynamics and species dependent. Herein, inspired by the fiber …

Bicuspid aortic valve (BAV) is a common congenital malformation of the aortic valve with
various structural characteristics. Different types of BAV can cause secondary aortic …

Transcatheter aortic valves provide superior systolic hemodynamic performance in terms of
valvular pressure gradient and effective orifice area compared with equivalent size surgical …

主动脉瓣发生病变时导致心排出量(cardiac output, CO) 减少, 而心排出量减少与主动脉瓣血流
动力学耦合作用, 引发瓣膜继发性疾病. 本文基于医学影像数据三维重构带有冠状动脉的主动脉 …

Anatomic pathologies such as stenosed or regurgitating heart valves and artificial organs
such as heart assist devices or heart valve prostheses are associated with non-physiological …

OBJECTIVES Subclinical leaflet thrombosis is a silent phenomenon commonly observed
following transcatheter aortic valve implantation. Leaflet thrombosis is associated with …