Duchenne muscular dystrophy (DMD), the severest form of muscular dystrophy, is
characterized by progressive muscle weakness with fatal outcomes most often before the …

This paper reviews the application of metabolomics in the early diagnosis of osteoporosis in
recent years. The authors searched electronic databases for the keywords “metabolomics”,“ …

Mitochondrial dysfunction and low nicotinamide adenine dinucleotide (NAD+) levels are
hallmarks of skeletal muscle ageing and sarcopenia,–, but it is unclear whether these …

Multiple studies have indicated that distinct metabolites are involved in the occurrence and
development of osteopenia (ON) and osteoporosis (OP); however, these metabolites in OP …

Purpose For early diagnosis of osteoporosis (OP), plasma metabolomics of OP was studied
by untargeted LC/GC− MS in a Chinese elderly population to find possible diagnostic …

Objective Branched chain amino acids (BCAA) are building blocks for protein, an essential
component of bone. However, the association of plasma levels of BCAA with fractures in …

Neural EGFL like 1 (NELL-1), is a secreted glycoprotein and stimulates osteogenic cell
differentiation and bone mineralization. This study aimed to explore the relationship …

Recent studies have provided links between glutamine metabolism and bone remodeling,
but little is known about its role in primary osteoporosis progression. We aimed to determine …

Objective The causal relationship between type 2 diabetes mellitus (T2DM) and
osteoporosis (OS) remains unclear. This study aims to investigate the causal relationship …

Background and aims Postmenopausal osteoporosis (PMO) and type 2 diabetes mellitus
(T2DM) frequently coexist in postmenopausal women. The study aimed to explore metabolic …