Unravelling the potential of mitochondria-targeted liposomes for enhanced cancer treatment

MS Khan, BHJ Gowda, WH Almalki, T Singh… - Drug discovery today, 2024 - Elsevier
Highlights•Mitochondria are involved in various physiochemical and biochemical
processes.•Owing to their crucial role in cellular metabolism, mitochondria are favored …

Mitochondria-targetable small molecule fluorescent probes for the detection of cancer-associated biomarkers: A review

X Yu, Y Huang, Y Tao, L Fan, Y Zhang - Analytica Chimica Acta, 2024 - Elsevier
Cancer represents a global threat to human health, and effective strategies for improved
cancer early diagnosis and treatment are urgently needed. The detection of tumor …

Theranostic magnetic nanoparticles: synthesis, properties, toxicity, and emerging trends for biomedical applications

A Setia, AK Mehata, AK Malik, MK Viswanadh… - Journal of Drug Delivery …, 2023 - Elsevier
Nanotechnology provides a wide range of nanosized devices, termed as nanotheranostics,
that are integrated with diagnostic and therapeutic properties for real-time monitoring and …

[HTML][HTML] Nanomedicine: Technologies and Applications

M Farrokhi, F Taheri, M Farrokhi, YEK Tosi… - Kindle, 2024 - preferpub.org
Nanomedicine is an innovative field that merges nanotechnology with medicine, aiming to
enhance diagnosis, treatment, and prevention of diseases at the molecular level. This …

Vitamin E TPGS-based nanomedicine, nanotheranostics, and targeted drug delivery: past, present, and future

AK Mehata, A Setia, AK Malik, R Hassani, HG Dailah… - Pharmaceutics, 2023 - mdpi.com
It has been seventy years since a water-soluble version of vitamin E called tocophersolan
(also known as TPGS) was produced; it was approved by USFDA in 1998 as an inactive …

Revitalizing Ancient Mitochondria with Nano‐Strategies: Mitochondria‐Remedying Nanodrugs Concentrate on Disease Control

X Long, M Liu, Y Nan, Q Chen, Z Xiao… - Advanced …, 2024 - Wiley Online Library
Mitochondria, widely known as the energy factories of eukaryotic cells, have a myriad of vital
functions across diverse cellular processes. Dysfunctions within mitochondria serve as …

[HTML][HTML] Herbal Theranostics: Controlled, Targeted Delivery and Imaging of Herbal Molecules

A Setia, B Vallamkonda, RR Challa, AK Mehata… - …, 2024 - ncbi.nlm.nih.gov
Modern medicine relies on a small number of key biologics, which can be found in nature
but require further characterization and purification before they can be used. Since the …

Mitochondria-targeted metal–organic frameworks for cancer treatment

TA Tabish, MZ Hussain, RA Fischer, A Casini - Materials Today, 2023 - Elsevier
Much of the progress in subcellular targeted therapy of cancer over the past years has been
driven by attacking disease cell's mitochondria. A paradigm, central to cancer biology is that …

[HTML][HTML] Protein transduction domain-mediated delivery of recombinant proteins and in vitro transcribed mRNAs for protein replacement therapy of human severe …

AN Miliotou, PF Foltopoulou, A Ingendoh-Tsakmakidis… - Pharmaceutics, 2023 - mdpi.com
Mitochondrial disorders represent a heterogeneous group of genetic disorders with
variations in severity and clinical outcomes, mostly characterized by respiratory chain …

Recent advances in mitochondria‐targeting theranostic agents

K Qian, S Gao, Z Jiang, Q Ding, Z Cheng - Exploration, 2024 - Wiley Online Library
For its vital role in maintaining cellular activity and survival, mitochondrion is highly involved
in various diseases, and several strategies to target mitochondria have been developed for …